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Wide Awake Trigger Finger Release Surgery

机译:广泛清醒触发手指松开手术

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Trigger finger is one of the most common conditions treated by hand surgeons with a lifetime risk estimated at 2.6% in the general population and 4% to 10% in patients with diabetes.7,8,13,17 It is generally characterized by pain, swelling, limitation of finger motion, and a triggering sensation caused by thickening of the A1 pulley and/or localized thickening of the tendon with resultant entrapment of the flexor tendons.14Conservative treatments are typically attempted first, including activity modification, splinting, physical therapy, nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroid injections, all of which have demonstrated varying degrees of success.13,14 If conservative management fails, surgical treatment is recommended that can result in up to a 100% success rate.3 Surgery is traditionally performed with or without sedation and a tourniquet, via a small incision at the level of the volar aspect of the metacarpal head followed by exposure and longitudinal release of the A1 pulley.A number of local anesthetics are readily available and utilized in hand surgery including but not limited to ropivacaine, Lidocaine and Marcaine. Recently, Exparel (Pacira, Parsippany, New Jersey) has been introduced which is an extended-release liposomal Marcaine-based analgesic that was granted FDA approval in 2011 for postsurgical analgesia through single-dose local administration into the surgical wound.15 The extended-release formulation consists of a microscopic, spherical, lipid-based delivery system, which allows for diffusion of Marcaine over an extended period, resulting in purported pain relief for up to 96 hours after surgery. Since its introduction, there have been numerous reports of successfully achieving prolonged pain relief with Exparel after various procedures such as breast augmentation, bunionectomy, hernia repairs, and total knee arthroplasty.1,9,21 However, currently there are no studies on Exparel in hand surgery.In this study, we prospectively evaluated the efficacy Lidocaine, Marcaine, or Marcaine with postoperative Exparel in controlling postoperative pain, opioid usage, and adverse reactions following trigger finger release (TFR) surgery performed wide awake without sedation or a tourniquet. The study hypothesis was that Exparel would result in lower postoperative pain and opioid consumption than with Lidocaine and Marcaine.
机译:扳机指是手外科医生治疗的最常见疾病之一,其终生风险在普通人群中估计为2.6%,在糖尿病患者中为4%至10%。7,8,13,17通常以疼痛,肿胀,手指活动受限以及由A1滑轮增厚和/或肌腱局部增厚并导致屈肌腱卡住引起的触发感觉。14通常首先尝试进行保守治疗,包括活动性改善,夹板,物理疗法,非甾体类抗炎药(NSAIDs)和皮质类固醇注射剂,都显示出不同程度的成功。13,14如果保守治疗失败,建议手术治疗可达到100%的成功率。3传统上,外科手术是通过在掌骨掌掌侧水平切开一个小切口,在有或没有镇静剂和止血带的情况下进行,然后进行暴露和纵向释放许多局部麻醉剂容易获得并用于手外科手术,包括但不限于罗哌卡因,利多卡因和可卡因。最近,Exparel(Pacira,Parsippany,New Jersey)上市,这是一种基于可卡因的脂质体缓释镇痛药,于2011年通过单剂量局部施用于手术伤口而获得FDA批准用于术后镇痛。15释放制剂由微观的,球形的,基于脂质的递送系统组成,该系统可延长可卡因的扩散时间,从而在手术后长达96小时内据称可缓解疼痛。自推出以来,已经有许多报道说在进行各种手术(例如隆胸,拇囊炎切除术,疝修补术和全膝关节置换术)后,Exparel可以成功地实现长时间的疼痛缓解。1、9、21然而,目前尚无关于Exparel的研究在这项研究中,我们前瞻性评估了利多卡因,可卡因或可卡因与术后Exparel在控制清醒,无镇静或止血带的触发手指释放(TFR)手术后控制术后疼痛,阿片类药物使用和不良反应的疗效。该研究假设是,与利多卡因和可卡因相比,Exparel可使术后疼痛和阿片类药物消耗减少。

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