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Ethnic Differences in Withdrawal of Life Support After Intracerebral Hemorrhage

机译:脑出血后撤离生命支持的种族差异

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Minorities are less likely to decide on withdrawal of life support (WOLS) after acute severe illness. However, the decision-making process for WOLS after intracerebral hemorrhage (ICH) among Native Hawaiians and other Pacific Islanders (NHOPI) has not been described. To address this gap in the literature, a retrospective study was conducted on consecutive spontaneous ICH patients admitted to a tertiary center in Honolulu between 2006 and 2010. The occurrence of WOLS and time-to-WOLS were the outcome measures. Unadjusted and multivariable logistic regression models were performed to determine associations between NHOPI ethnicity and WOLS. This study assessed 396 patients (18% NHOPI, 63% Asians, 15% non-Hispanic whites [NHW], 4% others) with ICH. NHOPI was associated with lower rate of WOLS than NHW in the univariate analysis (OR 0.35, 95% CI: 0.15, 0.80). However, NHOPI ethnicity was no longer significant when adjusted for age (OR 0.59, 95% CI: 0.25, 1.43) and in the fully adjusted model (OR 0.68, 95% CI: 0.20, 2.39). Although NHOPI with ICH were initially perceived to have less WOLS compared to NHW, this observed difference was largely driven by the younger age of NHOPI rather than from underlying cultural differences that are inherent to their ethnicity.
机译:少数人在急性严重疾病后不太可能决定退出生命支持(WOLS)。但是,尚未描述夏威夷土著人和其他太平洋岛民(NHOPI)脑出血(ICH)后WOLS的决策过程。为了弥补文献中的这一空白,我们对2006年至2010年间在檀香山三级中心收治的自发性ICH连续患者进行了回顾性研究。WOLS的发生和达到WOLS的时间是结果指标。进行未经调整的多变量logistic回归模型来确定NHOPI种族与WOLS之间的关联。这项研究评估了396例ICH患者(18%的NHOPI,63%的亚洲人,15%的非西班牙裔白人[NHW],其他4%)。在单变量分析中,NHOPI与WOLS的发生率低于NHW(OR 0.35,95%CI:0.15,0.80)。然而,在调整年龄(OR 0.59,95%CI:0.25,1.43)和完全调整模型(OR 0.68,95%CI:0.20,2.39)后,NHOPI种族不再显着。尽管最初认为具有ICH的NHOPI与NHW相比具有较少的WOLS,但这种观察到的差异很大程度上是由NHOPI的年龄较小而不是由其种族固有的潜在文化差异引起的。

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