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Rapid Diagnosis of Nonconvulsive Status Epilepticus Using Reduced-Lead Electroencephalography

机译:减少铅脑电图快速诊断非惊厥性癫痫持续状态

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Introduction: Electroencephalography (EEG) is indicated for diagnosing nonconvulsive status epilepticus (NCSE) in a patient who has altered level of consciousness after a motor seizure. A study in a neonatal population found 94% sensitivity and 78% specificity for detection of seizure using a single-lead device. This study aims to show that a reduced montage EEG would detect 90% of seizures detected on standard EEG. Methods: A portable Brainmaster EEG device was available in the emergency department (ED) at all times. Patients presenting to the ED with altered mental status and known history of seizure or a witnessed seizure having a standard EEG were eligible for this study. The emergency physician obtained informed consent from the legally authorized representative (LAR), while an ED technician attached the electrodes to the patient, and a research associate attached the electrodes to the wiring routing to the portable EEG module. A board-certified epileptologist interpreted the tracings via the Internet. Simultaneously, the emergency physician ordered a standard 23-lead EEG, which would be interpreted by the neurologist on call to read EEGs. We compared the epileptologist’s interpretation of the reduced montage EEG to the results of the 23-lead EEG, which was considered the gold standard for detecting seizures. Results: Twelve of 12 patients or 100% had the same findings on reduced-montage EEG as standard EEG. One of 12 patients or 8% had nonconvulsive seizure activity. Conclusion: The results are consistent with prior studies which have shown that 8-48% of patients who have had a motor seizure continue to have nonconvulsive seizure activity on EEG. This study suggests that a bedside reduced-montage EEG can be used to make the diagnosis of NCSE in the ED. Further study will be conducted to see if this technology can be applied to the inpatient neurological intensive care unit setting. [West J Emerg Med. 2015;16(3):442–446.].
机译:简介:脑电图(EEG)用于诊断运动发作后意识水平改变的患者的非惊厥性癫痫持续状态(NCSE)。一项针对新生儿的研究发现,使用单导联装置检测癫痫发作的敏感性为94%,特异性为78%。这项研究旨在表明,减少的蒙太奇EEG可以检测到在标准EEG上检测到的癫痫发作的90%。方法:随时可在急诊室使用便携式Brainmaster EEG设备。向ED提出精神状态改变和已知癫痫病史或目击性癫痫发作具有标准EEG的患者符合本研究的条件。急诊医师获得了合法授权代表(LAR)的知情同意,而ED技术人员将电极连接到患者,研究人员将电极连接到便携式EEG模块的布线。一名经过董事会认证的癫痫学家通过互联网解释了这些痕迹。同时,急诊医师订购了标准的23导联脑电图,由神经科医师在读取脑电图时进行解释。我们将癫痫学家对降低的蒙太奇EEG的解释与23导联EEG的结果进行了比较,后者被认为是检测癫痫发作的金标准。结果:12名患者中有12名或100%的蒙太奇降低型脑电图的发现与标准脑电图相同。 12名患者中有1名或8%患有非惊厥性癫痫发作。结论:该结果与先前的研究一致,该研究表明,运动癫痫发作的患者中有8-48%继续对脑电图具有非惊厥性癫痫发作活性。这项研究表明,床旁蒙太奇的脑电图可用于诊断急诊部的NCSE。将进行进一步的研究,以查看该技术是否可以应用于住院神经重症监护病房。 [西急救医学杂志。 2015; 16(3):442–446。]。

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