Theorical model of immune response in Helicobacter pylori ? gastric mucosa infection

摘要

H. pylori is a Gram -negative rod adaptad to survive in the gastric acid media, even for the whole life of a person with or without clinical manifestations of disease, but always producing an immune response with a broad spectrum (from mild inflammation infíltrate, ulcers to a gastric neoplasia). Considering bacterial pathogenicity determinants and a literature review, we try to propose a model of the relation among an immune response development against the H. pylori infection.