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Human Brucellosis presenting as endocarditis

机译:人布鲁氏菌病表现为心内膜炎

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Brucellosis is a bacterial disease of acute or insidious beginning, characterized by constant, intermittent or irregular fever, cefalagia, weakness, diaforesis, arthralgia, mialgias, and general discomfort (1), caused in animals and men by Brucella abortus , biotipo 1,6,9, melitensis biotipos 1,3, suis biotipos 1,5 and canis. (2.) OBJECTIVE : to present an individual case of brucellosis in a male patient. CLINICAL CASE: 46-year-old male patient from Mapiricure Cantaura, state Anzoátegui, worker of a slaughter house for 3 years, used to consuming raw milk and aborted cattle fetuses, his current disease started 1 month before consulting, when presented intermittent fever, mialgias, arthralgias, profuse perspiration, hiporexia, weakness and weight loss of approximately 16 kg in 1 month, At the time of consultation presented: Hf 86b/m, Rf 16rpm, BP 120/80 mmhg, febrile, diaforetic, eupneic without positive findings in the physical examination. Laboratory test: Hb 8,7g/dl, Hcto 25 % plt 112.000/mm leukocytes 3300mm, 47 segmented %, 53 % lymphocytes, vsg 80mm/1h, br 0,50mg/dl, bi 0,30mg/dl, bd 0,15mg/dl, alkaline phophatase 138 or, blood sugar 112g/dl, urea 32mg/dl, creatinine 0,7mg/dl uric acid 3, 6 mg/dl, negative hiv, vdrl i do not reactivate. Transthoracic ecocardiogram showed a round mobile image of 3,5 x 5 cm in the mitral, suggestive of vegetacion, producing severe mitral insufficiency. Blood samples gave positive tests for Brucella sp. The patient was subjected to a mitral valve replacement, with a satisfactory evolution. DISCUSSION: Brucellosis is a predominantly occupational zoonosis in workers of slaughter houses, veterinarians, farmers; whose period of incubation is variable from 5 to 60 days, more frequent from one to 2 months, and is acquired by direct contact with fabrics, urines, secretions, ingestion of lacteal products from infected animals .la recovery is the rule, but the disability is in the habit of being intense; without treatment the letalidad ranges in 2%.
机译:布鲁氏菌病是一种急性或隐匿性细菌性疾病,其特征是持续不断,间歇性或不规律的发烧,头疼,虚弱,糖尿病,关节痛,肌痛和一般不适(1),由流产布鲁氏菌引起,对人和动物都有危害,生物提纯1,6 ,9,melitensis生物体1,3,猪生物体1,5和犬。 (2.)目的:介绍一名男性患者布鲁氏菌病的个案。临床案例:来自Anzoátegui州Mapiricure Cantaura的一名46岁男性患者,曾是一家屠宰场的工人,工作了3年,过去经常食用生奶和流产的牛胎儿,他的当前疾病始于咨询前1个月,当时出现间歇性发烧,轻度偏头痛,关节痛,大量汗液,汗臭,虚弱和体重减轻,大约在1个月内减少16公斤,在就诊时显示:Hf 86b / m,Rf 16rpm,BP 120/80 mmhg,高热,有糖尿病,紫光,无阳性结果在体检中。实验室测试:Hb 8,7g / dl,Hcto 25%plt 112.000 / mm白细胞3300mm,47分段%,53%淋巴细胞,vsg 80mm / 1h,br 0,50mg / dl,bi 0,30mg / dl,bd 0, 15毫克/分升,碱性磷酸酶138或血糖112克/分升,尿素32毫克/分升,肌酸酐0.7毫克/分升尿酸3、6毫克​​/分升,HIV阴性,vdrl不会重新激活。经胸心电图检查显示二尖瓣圆形移动图像为3,5 x 5 cm,提示出现植物性病变,导致严重的二尖瓣关闭不全。血液样本对布鲁氏菌属进行了阳性测试。患者接受了二尖瓣置换术,并获得了满意的进展。讨论:布鲁氏菌病是屠宰场工人,兽医,农民的主要职业性人畜共患病。其潜伏期从5天到60天不等,更频繁的是从1个月到2个月不等,并且是通过直接接触被感染动物的织物,尿液,分泌物和摄入乳制品而获得的。有紧张的习惯;未经处理的莱来虫病占2%。

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