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Boron: An Overlooked Micronutrient that Plays an Important Role In Human Physiology

机译:硼:一种被忽略的微量营养素,在人体生理学中起重要作用

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Despite having many important functions, boron is generally overlooked by most nutritionists. This is surprising since boron accounts for 17 mg kg-1 of the earth’s crust with soils ranging in content from 3-100 mg kg-1 [1]. While early research suggested a role for boron in bone development, it is now known to play a far more extensive role in human health [2,3]. Studies feeding high doses of boron to experimental animals suggested it may be toxic to reproductive development. Based on these studies, the EU established a no observed adverse level (NOEL) for intake by humans. Basaran and co-workers [4], however, examined 204 male workers exposed to high boron levels in a factory in Turkey. No reproductive toxicity biomarkers were observed in any of the male workers in spite of their high boron blood levels which averaged around 223.89+69.49 ng/g. Occupational exposure to high levels of boron did not appear to have any detrimental effects which confirms previous studies reported in China [5,6].
机译:尽管硼具有许多重要功能,但大多数营养学家普遍忽略了硼。令人惊讶的是,硼占地壳的17 mg kg-1,土壤含量为3-100 mg kg-1 [1]。尽管早期的研究表明硼在骨骼发育中的作用,但现在已知它在人类健康中起着更为广泛的作用[2,3]。对实验动物饲喂高剂量硼的研究表明,硼可能对生殖发育有毒。根据这些研究,欧盟确定了人类摄入的未观察到的有害水平(NOEL)。但是,Basaran及其同事[4]在土耳其一家工厂检查了204位暴露于高硼水平的男性工人。尽管男性工人的硼血水平较高,平均约为223.89 + 69.49 ng / g,但未观察到生殖毒性生物标志物。职业暴露于高水平的硼似乎没有任何有害作用,这证实了中国先前的报道[5,6]。

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