RETROSPECTIVE ANALYSIS OF FACTORS AFFECTING INTENSIVE CARE UNIT MORTALITY IN PATIENTS OVER 75 YEARS OF AGE

摘要

Aim: This study aimed to investigate the value of the APACHE II scoring system in predictingmortality and identify the factors affecting mortality in advanced-age patients in the intensive careunit.Material and Methods: The medical records of patients >75 years of age who were hospitalizedat the intensive care unit of Dr. Lutfi Kirdar Education and Research Hospital between January 1,2012 and December 31, 2012 were examined. The patients were divided into two groups accordingto the diagnosis upon their hospitalization: medical and surgical. Total lymphocyte and leukocytecounts, as well as blood/serum levels of glucose, electrolytes and creatinine, were recorded on theday of hospitalization. Correlation of mortality with Glasgow Coma Scale, APACHE II score, andlaboratory findings was studied upon admission.Results: While mortality was associated with higher APACHE II score, factors such as advancedage on admission, higher serum creatinine levels, lower mean arterial pressure (<60 mmHg),need for inotropic agents within the first 24 hours, longer duration of mechanical ventilation, andpresence of acidosis during intensive care unit stay could increase risk of mortality. Regressionanalysis showed that APACHE II score was more related and could therefore serve as a betterpredictor of mortality than SAP 3 score.Conclusion: The predictors of intensive care unit mortality were found to be the same,regardless of the age group. Higher APACHE II score was a valuable scoring system for advancedagedpatients as well as for all age groups.