?LER? YA? HASTALARDA üROLOJ?K ENDOSKOP?K G?R???MLERDE ?K? FARKLI SEDASYON Y?NTEM?N?N KAR?ILA?TIRILMASI

摘要

Introduction: In this study, we evaluated the effectiveness and safety of intravenous propofol- fentanyl and ketamine-midazolam combinations for procedural sedation and analgesia in elderly patients undergoing urological endoscopic surgery. Materials and Method: This prospective study enrolled 80 patients aged 60-80 years ASA I-III requiring endoscopic urological procedures. Patients received intravenous bolus doses of either fentanyl 1 μg.kg-1 and propofol 1-2 mg.kg-1 in group P or ketamine 1-1.5 mg.kg-1 and midazolam 0.1 mg.kg-1 in group K titrated according to Ramsay sedation scale in the range of 3-4. Results: There were no differences in vital signs, operating times and demographic variables. Time to Aldrete score ≥8 was similar in two groups. Time to PADSS ≥9 was significantly longer in group K than group P (pConclusion: Hemodynamic changes and degrees of sedation showed that propofol-fentanyl and ketamine-midazolam combinations can safely be used in geriatric patients undergoing endoscopic urological procedures. However, in the propofol-fentanyl group the incidence of side effects were lower and the recovery period was shorter than the ketamine-midazolam group.