Evaluation of incidence of Non-Melanoma skin cancers in Esfahan

摘要

Non melanoma skin cancers (NMSC) are one of the most prevalent malignancies of humans. Although the mortality rate is not high for these cancers, they may cause high morbidity for the patients. In addition to the skin type, factors such as sun exposure, head and neck radiotherapy, inappropriate use of sunscreen and cultural changes may increase the incidence of these cancers.Aims: To determine the incidence of Non-Melanoma skin cancers in Esfahan:Settings and Design: This was a retrospective study. We used data of the cancer registry center for performing this study.Methods and Material: Statistical analysis used: Descriptional statistical tests and t-student test were used for statistical analysis.Results: Overall 1681 cases were registered that included 352 cases of SCC and 1329 cases with BCC. The incidence of NMSC was calculated to be 10.67/10`000 populationConclusions: Regarding topographic results, the most prevalent site for BCC were middle face and then head and neck and the least prevalent site was lower extremity. The most prevalent site for SCC was middle face and the least prevalent site was the trunk. Introduction Non melanoma skin cancers (NMSC) are one of the most prevalent malignancies of humans. Although the mortality rate is not high for these cancers, they may cause high morbidity for the patients. BCC can cause destruction of the nose, eyes, paranasal sinuses, and even can invade dura and brain (1).SCC,in addition to local destruction, can metastasize and even lead to death. Although most cases of NMSC are observed in fair skin people, this condition is still at the top of malignancy list in the ethnical skin types (2).In addition to the skin type, factors such as sun exposure, head and neck radiotherapy, inappropriate use of sunscreen and cultural changes may increase the incidence of these cancers.In this study we evaluated the incidence of the NMSC in Esfahan continent as the sample community of Iran. Subjects and Methods This was a retrospective study in that digital information of Esfahan cancer registry center was used. Digital information was analyzed from data that was registered between years1997-2001 and were grouped by age, sex, demographic and topographic characteristic of skin cancer. In this center, ICD0 codes were used for cancer types, its location and patients demographic characteristics.The cases of the mucosal and genital cancers were excluded. We considered NMSC as the sum of both SCC and BCC excluding cases of mucosal and genital cancers.The mean population of the Esfahan continent was 3'937'593 at the time of the study, including 2'027884 males and 1'909'709 were female. Results Overall 1681 cases were registered that included 352 cases of SCC and 1329 cases with BCC. The population of Esfahan was estimated to be 3`937`593, the incidence of NMSC was calculated to be 10.67/10`000 population. Sex distribution of the NMSC is shown in table.1. These cancers were most prevalent in the 5th-8th decade.(table.2)Regarding topographic results, the most prevalent site for BCC were middle face and then head and neck and the least prevalent site was lower extremity. The most prevalent site for SCC was middle face and the least prevalent site was the trunk. The number of mucosal SCC was 223 (table 3).