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Fluoritop-SR? On Demineratlization Inhibitory Effect

机译:Fluoritop-SR?论脱矿抑制作用

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Dear Sir, Fluoride in trace amounts increases the resistance of tooth structures to demineralization and therefore a particularly important consideration for caries prevention. This study was conducted to demineralization inhibitory effect of Fluoritop– SR?. Calcium and phosphorus dissolutions were estimated of measure of demineralization inhibitory effects the demineralization inhibitory effects. Fluoride is available during cycles of tooth demineralization, it is a major factor in reduced caries activity1. Various fluoride varnishes, gel are available and are successful in preventing caries. Additional research on fluoride varnishes is needed, the use of a fluoride varnish as a caries preventive agent should be expanded because it has advantages over other topical fluoride vehicles in terms of safety, ease of application and fluoride concentration at the enamel effect2. Most of the loss may occur within the first 24 hours, to achieve prolonged fluoride action in the mouth.3 Twenty five freshly extracted permanent teeth each without any caries lesions or restorations were selected for study. The teeth were first cleaned with pumice slurry and polishing brush in a slowly rotating hand piece. The teeth were then thoroughly washed under running water. Each tooth was cut into four sections using a high diamond tipped disc. The sections were again rinsed under running water to clean them of debris and particles. They were than gently air dried. The dentin portions of each section covered with modeling wax. Only the enamel portion were exposed. Of the four enamel sections one left without any fluoride varnish application and served as a controls. The camel haired brushes were used for applying Fluoritip– SR?. One layer of varnish was applied and allowed to dry and remain in place for 24 hours. Artificial saliva was prepared in biochemistry department of Pt. B.D. Sharma, Rohtak. Double deionized water was used in the preparation so no fluoride ions were present in composition. Synthetic salivary pH was adjusted by the portable standard digital pH meter using hydrochloric acid and sodium hydroxide. 1000 ml solution each of synthetic saliva at two different pH 5.2 and 6.8 were prepared. After 48 hours application of fluoride varnishes, one tooth section of each group for every tooth used in the study was immersed in 30 ml of the synthetic saliva at the pH 5.2 and the other section was immersed in 30 ml of synthetic saliva at pH 6.8. The 30 ml sample of synthetic saliva at two different pH 5.2 and 6.8 (without any tooth section) were also tested to estimate the calcium and phosphorous contents at the beginning of the study. The phosphorous and calcium ion content of synthetic salivary samples at the two different pH 5.2 and 6.8 were measured. It was found to be nil for both samples. Calcium and phosphorous ions released over the 24 hour period were measured by speatrophotometry. Calcium and phosphorous ions were measured at the atomic level and expressed as parts as million (ppm). The entire data collected was subjected to statistical analysis by using computer software package SPSS/PC version 7.0.
机译:亲爱的先生,微量的氟化物会增加牙齿结构抗脱矿质的能力,因此对于预防龋齿尤为重要。这项研究是为了对Fluoritop–SR?的去矿质抑制作用进行的。估计钙和磷的溶解度是衡量脱盐抑制作用的量。在牙齿脱盐的过程中可以使用氟化物,这是减少龋齿活动的主要因素1。可以使用各种氟化物清漆,凝胶,并且可以成功地预防龋齿。需要对氟化物清漆进行更多的研究,应扩大氟化物清漆作为防龋剂的用途,因为它在安全性,易用性和珐琅效果上的氟化物浓度方面优于其他局部氟化物载体。大多数损失可能发生在最初的24小时内,以延长口腔中的氟化物作用。3选择了25颗刚拔出的恒牙,每颗均没有任何龋齿或修复体。首先在缓慢旋转的手柄中用浮石浆和抛光刷清洁牙齿。然后在流水下彻底清洗牙齿。使用高金刚石尖端的圆盘将每颗牙齿切成四个部分。将切片再次在流水下冲洗,以清除碎片和颗粒。然后将它们轻轻风干。每个部分的牙本质部分覆盖有造型蜡。仅釉质部分被暴露。在四个搪瓷部分中,一个不使用任何氟化清漆,作为对照。骆驼毛刷用于应用Fluoritip–SR®。施加一层清漆,使其干燥并保持原位24小时。人工唾液是在Pt的生物化学部门准备的。公元前夏尔马,罗塔克。制备中使用了双去离子水,因此组合物中不存在氟离子。通过便携式标准数字pH计,使用盐酸和氢氧化钠调节唾液的合成pH。分别制备了两种不同pH值5.2和6.8的合成唾液1000 ml溶液。在应用氟化清漆48小时后,将每组用于研究的每颗牙齿的一个牙齿部分浸入pH值为5.2的30毫升合成唾液中,另一部分浸入pH值为6.8的30毫升合成唾液中。在研究开始时,还测试了30 ml两种不同pH值5.2和6.8(无任何牙齿切面)的合成唾液样品,以评估钙和磷的含量。在两个不同的pH 5.2和6.8下测量了合成唾液样品中的磷和钙离子含量。发现两个样品均为零。通过分光光度法测量在24小时内释放的钙和磷离子。钙和磷离子在原子水平上进行测量,并表示为百万分之一(ppm)。使用计算机软件包SPSS / PC 7.0版对收集的全部数据进行统计分析。

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