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Narrative review of contemporary treatment options in the care of patients with obstructive sleep apnoea

机译:阻塞性睡眠呼吸暂停患者现代治疗选择的叙事回顾

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Snoring and obstructive sleep apnoea (OSA) are increasingly common conditions, and confer a significant health and socioeconomic burden. Furthermore, untreated OSA represents a significant mortality risk. Patients require careful assessment, including detailed clinical history and examination, sleep study and drug-induced sleep endoscopy (DISE). Although nasal continuous positive airway pressure (nCPAP) is the gold standard treatment for moderate and severe OSA, multidisciplinary team assessment is often required to develop the best treatment plan for an individual, especially when nasal CPAP is poorly tolerated. There is a wide range of medical and surgical treatment options, and following appropriate patient selection and assessment, a focused site-specific, often multilevel, intervention is indicated. There is an increasing body of evidence in the literature supporting these multilevel interventions and with agreement on standardized outcome measures more trials are likely to improve the robustness of these data further.
机译:打和阻塞性睡眠呼吸暂停(OSA)越来越常见,并给健康和社会经济带来沉重负担。此外,未治疗的OSA代表重大的死亡风险。患者需要仔细评估,包括详细的临床病史和检查,睡眠研究和药物诱发的睡眠内窥镜检查(DISE)。尽管鼻持续气道正压通气(nCPAP)是中度和重度OSA的金标准治疗方法,但经常需要进行多学科团队评估以制定针对个人的最佳治疗方案,尤其是当鼻CPAP耐受性差时。药物和手术治疗的选择范围很广,在对患者进行适当的选择和评估之后,需要进行针对性的针对特定地点的干预,通常是多层次的。文献中越来越多的证据支持这些多层次干预措施,并且在标准化结果指标上达成一致,更多的试验可能会进一步改善这些数据的稳健性。

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