HCV AND HBV INFECTION WITH A COMPARATIVE STUDY TO ASSESS THE POOR PROGNOSTIC FACTORS AND IN-HOSPITAL MORTALITY RATE

摘要

Objectives: The aim behind this study was to scientifically assess the poor prognostic factors and in-hospital mortality rate in patients infected with HCV and HBV infection with liver cirrhosis. Study Design: Comparative hospital based study. Setting: Gastroenterology and hepatology dedicated center, Asian Institute of Medical Sciences (AIMS), Hyderabad. Period: Thirty one months from 1 st October 2012 to 31 st May 2015. Patients and Methods: 419 participants between the ages of 20 to 80 years including both male and female and diagnosed either with HCV or HBV infection along with cirrhosis were included. Data were entered and analyzed by using Statistical Package for the Social Sciences version 20.0. Results: Out of total 419 patients, the mean age and S.D. of HBV patients were 41.21 ± 11.77 and HCV patients were 50.44 ± 10.07 years. The overall mortality rate was 11.69% (N = 49) among them patients with of HBV infection had a comparatively higher mortality rate than patients with HCV infection, 13.07% and 11.07%, respectively. The most common risk factors observed in our study were Hepatorenal syndrome (41.17%) in HCV cirrhotics and hematemesis (34.37%) in HCV cirrhotic patients. Conclusion: Our study shows that overall mortality is greater in HBV cirrhotic patients than with HCV cirrhotics. Poor in-hospital mortality factors vary in both HBV and HCV related cirrhotic patients and this discrepancy in the observation is universally observed.