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Growth Hormone Receptor (GHR) Exon 3 Polymorphism Status Detection by Dual-Enzyme-Linked Immunosorbent Assay (ELISA)

机译:通过双酶联免疫吸附测定(ELISA)检测生长激素受体(GHR)外显子3多态性状态

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Context:GH receptor (GHR) exon 3-deleted/full-length (d3/fl) polymorphism has been proposed to affect the responsiveness to GH therapy. Conventional multiplex PCR genotyping method for this polymorphism detection requires DNA samples, which may be difficult to obtain due to ethical and procedural issues and may limit further studies into the role of this polymorphism in health and disease.
机译:背景:已提出GH受体(GHR)外显子3缺失/全长(d3 / fl)多态性影响GH治疗的反应性。用于这种多态性检测的常规多重PCR基因分型方法需要DNA样本,由于道德和程序问题,这种样本可能难以获得,并且可能限制对该多态性在健康和疾病中的作用的进一步研究。

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