Reduction in the Risk of Clinical Fractures After a Single Dose of Zoledronic Acid 5 Milligrams

摘要

Context:Annual infusions of zoledronic acid 5 mg over 3 years have been shown to reduce fracture incidence. There is now evidence that the effects of a single dose of zoledronic acid on bone mineral density and bone turnover last for much more than a year. Whether this is associated with sustained fracture prevention is not known.