Effects of Recombinant Human Growth Hormone Therapy on Bone Mineral Density in Adults With Growth Hormone Deficiency: A Meta-Analysis

Maya Barake; Anne Klibanski; Nicholas A. Tritos

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Effects of Recombinant Human Growth Hormone Therapy on Bone Mineral Density in Adults With Growth Hormone Deficiency: A Meta-Analysis

机译：重组人生长激素治疗对生长激素缺乏症成年人骨矿物质密度的影响：荟萃分析

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Objective:GH deficiency is associated with decreased bone mineral density (BMD) and increased fracture risk. Because the effects of recombinant human GH (rhGH) therapy on BMD and bone mineral content have not been systematically investigated, we conducted a meta-analysis of pertinent studies.

机译：目的：生长激素缺乏症与降低骨矿物质密度（BMD）和增加骨折风险有关。由于尚未系统研究重组人GH（rhGH）治疗对BMD和骨矿物质含量的影响，因此我们对相关研究进行了荟萃分析。

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《The journal of clinical endocrinology and metabolism》 |2014年第3期|共9页
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Maya Barake; Anne Klibanski; Nicholas A. Tritos;
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1. Effects of recombinant growth hormone (GH) treatment on bone mineral density and body composition in adults with childhood onset growth hormone deficiency. [J] . Sartorio A, Ortolani S, Conti A, Journal of Endocrinological Investigation: Official Journal of the Italian Society of Endocrinology . 1996,第8期

机译：重组生长激素（GH）治疗对成年儿童生长激素缺乏症成人的骨矿物质密度和身体组成的影响。
2. Effects of recombinant growth hormone (GH) treatment on bone mineral density and body composition in adults with childhood onset growth hormone deficiency. [J] . Sartorio A, Ortolani S, Conti A, Journal of Endocrinological Investigation: Official Journal of the Italian Society of Endocrinology . 1996,第8期

机译：重组生长激素（GH）治疗对成年儿童生长激素缺乏症成人的骨矿物质密度和身体组成的影响。
3. Effects of Growth Hormone Replacement Therapy on Bone Mineral Density in Growth Hormone Deficient Adults; A Meta-Analysis [J] . Peng Xue, Yan Wang, Jie Yang, International journal of endocrinology . 2013,第Pta1期

机译：生长激素替代疗法对生长激素缺乏症成年人骨矿物质密度的影响;荟萃分析
4. Calcium phosphate guides bone formation in critical size defects but no effect of locally delivered recombinant human growth hormone in a canine gap model [C] . Zippor B, Kold S, Rahbek O, Annual meeting of the Society For Biomaterials . 2003

机译：磷酸钙可指导骨骼形成关键尺寸的缺损，但在犬间隙模型中对局部递送的重组人生长激素没有影响
5. Bone mineral density, bone remodeling, insulin-like growth factors, hormone replacement therapy, and exercise training in postmenopausal women [D] . Milliken, Laura Ann. 1998

机译：绝经后妇女的骨矿物质密度，骨骼重塑，胰岛素样生长因子，激素替代疗法和运动训练
6. Effects of Growth Hormone Replacement Therapy on Bone Mineral Density in Growth Hormone Deficient Adults: A Meta-Analysis [O] . Peng Xue, Yan Wang, Jie Yang, 2013

机译：生长激素替代疗法对生长激素缺乏症成年人骨矿物质密度的影响：一项荟萃分析
7. Effects of Recombinant Human Growth Hormone Therapy on Bone Mineral Density in Adults With Growth Hormone Deficiency: A Meta-Analysis [O] . Maya Barake, Anne Klibanski, Nicholas A. Tritos 2014

机译：重组人体生长激素治疗对生长激素缺乏的成人骨密度的影响：META分析

Effects of Recombinant Human Growth Hormone Therapy on Bone Mineral Density in Adults With Growth Hormone Deficiency: A Meta-Analysis

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