Obestatin Levels Are Associated With C-Peptide and Antiinsulin Antibodies at the Onset, Whereas Unacylated and Acylated Ghrelin Levels Are Not Predictive of Long-Term Metabolic Control in Children With Type 1 Diabetes

摘要

Context and Objective:Ghrelin secretion is altered at the onset and after the start of insulin therapy in children with type 1 diabetes. Contemporary regulation of acylated ghrelin (AG), unacylated ghrelin (UAG), and obestatin (OBST) remains undefined in this disease. It is unknown as to whether they could be good predictors of changes in glucose and metabolic control.