首页> 外文期刊>The journal of clinical endocrinology and metabolism >Zoledronic Acid Acutely Increases Sclerostin Serum Levels in Women With Postmenopausal Osteoporosis
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Zoledronic Acid Acutely Increases Sclerostin Serum Levels in Women With Postmenopausal Osteoporosis

机译:唑来膦酸可急性增加绝经后骨质疏松症妇女的硬化素血清水平

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Context:Sclerostin is a circulating inhibitor of the Wnt-signaling pathway produced by osteocytes, which acts as a negative regulator of bone formation. Effects of zoledronic acid on sclerostin serum levels in postmenopausal osteoporosis are unknown.
机译:背景:硬化蛋白是骨细胞产生的Wnt信号通路的循环抑制剂,可作为骨形成的负调节剂。唑来膦酸对绝经后骨质疏松症中硬化蛋白血清水平的影响尚不清楚。

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