A TSHr-LH/CGr Chimera that Measures Functional TSAb in Graves' Disease

Cesidio Giuliani; Dominique Cerrone; Norikazu Harii; Mark Thornton; Leonard D. Kohn; Nilesh M. Dagia; Emilio Fiore; Ines Bucci; Tyler Chamblin; Paolo Vitti; Fabrizio Monaco; Giorgio Napolitano

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A TSHr-LH/CGr Chimera that Measures Functional TSAb in Graves' Disease

机译：TSHr-LH / CGr嵌合体，可测量Graves病中的功能性TSAb

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Context:Stimulating thyrotropin receptor (TSHr) autoantibodies (TSAb) are the cause of hyperthyroidism in Graves' disease. In a patient's serum, TSAb can coexist with antagonist TSHr autoantibodies that block TSAb stimulatory activity (TSBAb); both can vary in amount and time.

机译：背景：促甲状腺激素受体（TSHr）自身抗体（TSAb）是Graves病甲亢的原因。在患者的血清中，TSAb可以与阻断TSAb刺激活性（TSBAb）的拮抗剂TSHr自身抗体共存。两者都可以在数量和时间上有所不同。

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《The journal of clinical endocrinology and metabolism》 |2012年第7期|共10页
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Cesidio Giuliani; Dominique Cerrone; Norikazu Harii; Mark Thornton; Leonard D. Kohn; Nilesh M. Dagia; Emilio Fiore; Ines Bucci; Tyler Chamblin; Paolo Vitti; Fabrizio Monaco; Giorgio Napolitano;
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1. A TSHr-LH/CGr Chimera that Measures Functional TSAb in Graves' Disease [J] . Cesidio Giuliani, Dominique Cerrone, Norikazu Harii, The journal of clinical endocrinology and metabolism . 2012,第7期

机译：TSHr-LH / CGr嵌合体，可测量Graves病中的功能性TSAb
2. A TSHR-LH/CGR Chimera that Measures Functional Thyroid-Stimulating Autoantibodies (TSAb) Can Predict Remission or Recurrence in Graves' Patients Undergoing Antithyroid Drug (ATD) Treatment [J] . Cesidio Giuliani, Dominique Cerrone, Norikazu Harii, The journal of clinical endocrinology and metabolism . 2012,第7期

机译：衡量功能性甲状腺刺激的自身抗体（TSAB）的TSHR-LH / CGR Chimera可以预测经过抗胆汁药物（ATD）治疗的坟墓患者的缓解或复发
3. Graves’ Disease TSHR-Stimulating Antibodies (TSAbs) Induce the Activation of Immature Thymocytes: A Clue to the Riddle of TSAbs Generation? [J] . Mireia Giménez-Barcons, Roger Colobran, Ana Gómez-Pau, The journal of immunology . 2015,第9期

机译：格雷夫斯病刺激TSHR的抗体（TSAb）诱导未成熟胸腺细胞的激活：这是TSAb产生之谜的线索吗？
4. Blood disease and panama disease: two newly introduced and grave threats to banana production on the island of New Guinea [C] . R. I. Davis, N. Y. Moore, M. Fegan Workshop of the Australian Centre for International Agricultural Research . 2000

机译：血液疾病和巴拿马病：两个新引入的和严重威胁在新几内亚岛上的香蕉生产
5. Nitrate Chimeras: A New Class of Disease-Modifying Agents for the Treatment of Alzheimer's Disease. [D] . VandeVrede, Lawren. 2014

机译：硝酸盐嵌合体：治疗阿尔茨海默氏病的新型疾病改良剂。
6. Changes of TSH-Stimulation Blocking Antibody (TSBAb) and Thyroid Stimulating Antibody (TSAb) Over 10 Years in 34 TSBAb-Positive Patients with Hypothyroidism and in 98 TSAb-Positive Graves Patients with Hyperthyroidism: Reevaluation of TSBAb and TSAb in TSH-Receptor-Antibody (TRAb)-Positive Patients [O] . Nobuyuki Takasu, Mina Matsushita 2012

机译：34例甲状腺功能减退的TSBAb阳性患者和98例甲状腺功能亢进的Graves甲状腺功能亢进患者中10年来TSH刺激阻断抗体（TSBAb）和甲状腺刺激抗体（TSAb）的变化：TSHb和TSAb在TSH受体中的重新评估抗体（TRAb）阳性患者
7. A TSHr-LH/CGr chimera that measures functional TSAb in Graves' disease. [O] . Giuliani C, Cerrone D, Harii N, 2012

机译：TSHr-LH / CGr嵌合体，可测量Graves病中的功能性TSAb。

A TSHr-LH/CGr Chimera that Measures Functional TSAb in Graves' Disease

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