Bone Mineral Density and Testicular Failure: Evidence for a Role of Vitamin D 25-Hydroxylase in Human Testis

Carlo Foresta; Giacomo Strapazzon; Luca De Toni; Lisa Perilli; Antonella Di Mambro; Barbara Muciaccia; Leonardo Sartori; Riccardo Selice

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Bone Mineral Density and Testicular Failure: Evidence for a Role of Vitamin D 25-Hydroxylase in Human Testis

机译：骨矿物质密度和睾丸衰竭：维生素D 25羟化酶在人类睾丸中的作用的证据。

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Working Hypothesis:Mutations in the CYP2R1 gene, highly expressed in the testis and encoding vitamin D 25-hydroxylase, result in a vitamin D deficiency and a defective calcium homeostasis leading to rickets.

机译：工作假设：CYP2R1基因突变在睾丸中高表达并编码维生素D 25-羟化酶，导致维生素D缺乏和钙稳态失衡，导致病。

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《The journal of clinical endocrinology and metabolism》 |2011年第4期|共7页
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Carlo Foresta; Giacomo Strapazzon; Luca De Toni; Lisa Perilli; Antonella Di Mambro; Barbara Muciaccia; Leonardo Sartori; Riccardo Selice;
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1. Bone Mineral Density and Testicular Failure: Evidence for a Role of Vitamin D 25-Hydroxylase in Human Testis [J] . Carlo Foresta, Giacomo Strapazzon, Luca De Toni, The journal of clinical endocrinology and metabolism . 2011,第4期

机译：骨矿物质密度和睾丸衰竭：维生素D 25羟化酶在人类睾丸中的作用的证据。
2. Evidence for a major gene for bone mineral density/content in human pedigrees identified via probands with extreme bone mineral density. [J] . Deng HW, Livshits G, Yakovenko K, Annals of Human Genetics . 2002,第Pta1期

机译：通过具有极高骨矿物质密度的先证者鉴定的人类谱系中骨矿物质密度/含量的主要基因的证据。
3. Vitamin K1 intake is associated with higher bone mineral density and reduced bone resorption in early postmenopausal Scottish women: no evidence of gene-nutrient interaction with apolipoprotein E polymorphisms. [J] . Macdonald HM, McGuigan FE, Lanham-New SA, The American Journal of Clinical Nutrition: Official Journal of the American Society for Clinical Nutrition . 2008,第5期

机译：维生素K1的摄入与绝经后的早期苏格兰妇女中较高的骨矿物质密度和降低的骨吸收有关：没有证据表明基因营养与载脂蛋白E多态性相互作用。
4. HETEROGENEITY OF BONE MINERAL DENSITY AND FATIGUE FAILURE OF HUMAN VERTEBRAE [C] . Yener N. Yeni, Laila M. Poisson, Michael J. Flynn ASME summer bioengineering conference;SBC2012 . 2012

机译：骨密度的异质性与人椎骨的疲劳破坏
5. Relations of bone mineral density, blood lead levels, bone lead levels and the apolipoprotein E and vitamin D receptor genotypes [D] . Theppeang, Keson 2008

机译：骨矿物质密度，血铅水平，骨铅水平与载脂蛋白E和维生素D受体基因型的关系
6. Vitamin D Deficiency and Low Bone Mineral Density in Pediatric and Young Adult Intestinal Failure [O] . Agozie C Ubesie, James E Heubi, Samuel A Kocoshis, -1

机译：小儿和年轻成人肠衰竭的维生素D缺乏症和低骨矿物质密度
7. Bone Mineral Density and Testicular Failure: Evidence for a Role of Vitamin D 25-Hydroxylase in Human Testis [O] . C. FORESTA, STRAPAZZON G, DE TONI L, 2011

机译：骨矿物质密度和睾丸衰竭：维生素D 25羟化酶在人类睾丸中的作用的证据。

Bone Mineral Density and Testicular Failure: Evidence for a Role of Vitamin D 25-Hydroxylase in Human Testis

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