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Epidemiology of urino-genital trichomoniasis in a north-eastern State, Nigeria

机译:尼日利亚东北州尿液生殖器滴虫的流行病学

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There have been a paucity of published data on the distribution of urino-genital trichomoniasis in this part of the globe. The study was intended to determine the epidemiology of the infection so as to serve as baseline information for future studies in this part of the world. One thousand five hundred and twenty subjects aged 15-64 years, were randomly selected from some health facilities in the state. Ethical approval from the State Ministry of Health was obtained and informed consent of the subjects was sought before commencing the research. Culture, staining and wet preparation techniques were employed to identify the causative parasite. An overall prevalence of 2.6%, was recorded which varied significantly by settlement status (P<0.005). No significant difference in the infection rate in relation to Age (P>0.05), gender (P>0.005) and marital status of the subjects (P>0.05). Although relatively low rate of the infection was recorded in this study, adequate management and control of the infection was advocated to prevent future epidemic of the infection. Introduction Urino-genital trichomoniasis can be defined as an infection of male and female urino-genital tracts by Trichomonas vaginalis. Over 120 million females are infected annually worldwide while the prevalence ranges between 2% and 50% among women in Africa (1). Inspite of frequent reports on the public health importance of urino-genital trichomoniasis, its prevalence still continues to rise in many countries of the world (2). Trichomonas vaginalis, the aetiological agent of urino-genital trichomoniasis, is a flagellated protozoan, site-specific and mostly sexually transmitted human parasite. It was first identified in 1836 as a harmless vagina commensal, but was later associated with vaginal discharge hence said to be pathogenic. (3). The infection is common among sexually active males and females especially during the child bearing age. It is frequently encountered among 50% of women complaining of abnormal vaginal discharge and itching. (4). Vaginal trichomoniasis may be transmitted to neonates in a similar way as other genital infections during birth (5).In new York, a study carried out among some women in the city reported (6) 47% prevalence rate while in another, conducted between 1992 and 1995 among a cohort of 212 women in Los Angels, urino-genital trichomoniasis was the most frequently identified sexually transmitted infection with 19.4% prevalence rate(7). In Kenya, a study reported(8) a prevalence of 34.4% of urino-genital trichomoniasis in the country. In Nigeria a research conducted at Lagos University Teaching Hospital showed trichomoniasis prevalence rate of 8.2% among the women sampled (9). At University Hospital, Ibadan a prevalence rate of 20.5% out of 151 women attending infertility clinic was recorded. In Jos, Adebayo recorded (10) 12.3% prevalence rate of Trichomonas vaginalis from pregnant women attending gynaecology clinic (11), while 24.1% was recorded in a similar work done among pregnant women in the same city (12).However, there have been a paucity of published data on the distribution of the infection in Adamawa State, Nigeria. This study was therefore focused on the determination of the epidemiological distribution of the infection in the state with the aim of providing baseline information for future studies on urino-genital trichomoniasis in north-eastern Nigeria. Subjects and Methods Study PopulationThe study was conducted between January 2006 and October 2007 in rural and urban settlements of Adamawa State, Nigeria. It was health-centre based to avoid inadequate sample that may arise from stigma attached to sexually transmitted infection. A total of 1520 subjects aged 15-64 years were randomly examined among pregnant and non-pregnant women, sick and apparently health men and some women attending family planning clinics in the selected health centres. Prior to the commencement of sample collection ethical approvals were obtained from a
机译:在全球的这一地区,关于尿液-生殖器滴虫病分布的公开数据很少。该研究旨在确定感染的流行病学,以便为该地区的未来研究提供基线信息。从该州的一些医疗机构中随机选择了1520名年龄在15-64岁之间的受试者。在开始研究之前,已获得国家卫生部的伦理批准,并征得受试者的知情同意。采用培养,染色和湿法制备技术鉴定病原体。总体患病率为2.6%,随定居状况的不同而有显着差异(P <0.005)。感染率与受试者的年龄(P> 0.05),性别(P> 0.005)和婚姻状况(P> 0.05)没有显着差异。尽管在这项研究中记录了相对较低的感染率,但提倡对感染的适当管理和控制以防止将来感染的流行。引言泌尿生殖道毛滴虫病可定义为阴道毛滴虫感染的男性和女性泌尿生殖道。全世界每年有超过1.2亿女性被感染,而非洲女性的患病率介于2%至50%之间(1)。尽管关于尿液生殖器滴虫的公共卫生重要性的报道频繁,但在世界许多国家,其流行率仍在继续上升(2)。阴道毛滴虫是泌尿生殖器滴虫的病原体,是一种鞭毛的原生动物,是特定部位的,主要是通过性传播的人类寄生虫。它最初于1836年被鉴定为对阴道无害的共生病,但后来与白带病相关,因此被认为是致病性的。 (3)。这种感染在性活跃的男性和女性中很普遍,尤其是在生育年龄的儿童中。 50%抱怨阴道分泌物异常和瘙痒的女性经常遇到这种情况。 (4)。阴道毛滴虫病可能以与出生时其他生殖器感染相似的方式传播给新生儿(5)。在纽约,该市一些女性进行的一项研究报告说(6)患病率为47%,而在另一位于1992年之间进行的研究中1995年,在洛杉矶的212名妇女队列中,尿路生殖器滴虫是最常见的性传播感染,患病率为19.4%(7)。在肯尼亚,一项研究报道[8],该国的尿液生殖器毛滴虫病患病率为34.4%。在尼日利亚,在拉各斯大学教学医院进行的一项研究显示,抽样妇女的毛滴虫病患病率为8.2%(9)。在伊巴丹大学医院,在不孕症诊所的151名妇女中,患病率为20.5%。在乔斯(Jos),阿德巴约(Adebayo)记录(10)前往妇科诊所的孕妇的阴道毛滴虫患病率(12.3)(11),而在同一城市的孕妇中进行的类似工作记录的阴道滴虫患病率(24.1%)(12)。有关尼日利亚阿达玛瓦州感染分布的公开数据很少。因此,本研究的重点是确定该州感染的流行病学分布,旨在为尼日利亚东北部的泌尿生殖器滴虫病的未来研究提供基准信息。受试者与方法研究人群该研究于2006年1月至2007年10月在尼日利亚阿达玛瓦州的农村和城市居住区进行。以健康为中心,避免因性传播感染造成的污名而导致样本不足。共有1520名年龄在15-64岁之间的受试者在怀孕和未怀孕的妇女,患病的人和显然健康的男子以及在选定的卫生中心就诊的计划生育诊所的一些妇女中进行了随机检查。在开始样品采集之前,已从

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