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Angiectatic Nasal Polyp - The Great Imitator

机译:血管鼻息肉-伟大的模仿者

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Introduction: Angiectatic nasal polyps are a rare and distinct type of inflammatory sinonasal polyp, which can clinically and radiologically mimic a sinonasal neoplasm. We describe a unique case of an angiectatic nasal polyp in an 80 year old lady presenting with recurrent epistaxis and radiological features suggestive of an inverted papilloma.Management: Initial biopsies proved inconclusive. Complete resection was performed through an endoscopic medial maxillectomy approach based on the suspicion of an inverted papilloma. Initially, the histopathology was reported as an inflammatory polyp but this was subsequently revised to an angiectatic nasal polyp. Histopathology Findings: A well-defined polyp with stromal degenerative hyaline change, stromal haemorrhage and telangiectasia, lined by flattened surface epithelium.Conclusion: Angiectatic nasal polyps are a rare pathological entity and as such can cause a significant diagnostic dilemma as illustrated in this case. Therefore, an awareness of different clinical presentations and distinct histopathological features is important in establishing an early definitive diagnosis. Furthermore, there is little precedent in the literature to guide management in such a case, and we therefore consider this report to be noteworthy and instructive in this respect. Introduction Angiectatic nasal polyps, also known as angiomatous nasal polyps, are rare and only account for approximately 5% of all inflammatory sinonasal polyps.1 Indeed only a very small number have been reported within the literature to date. These polyps present in a myriad of ways, often simulating other pathologies including malignancy.We present the case of an 80 year old patient presenting with a unilateral nasal mass and epistaxis in whom the radiological findings were initially suggestive of an inverted papilloma, but the histopathological findings subsequently revealed an angiectatic nasal polyp. Case report An 80 year old lady presented to accident & emergency (A&E) with a 5 week history of recurrent epistaxis. Inability to control the bleeding with conservative measures during the presenting episode led to anterior nasal packing by the referring ENT unit. Her co-morbidities included hypertension which was well controlled with anti-hypertensives, and previous transient ischaemic attacks for which she was on Aspirin.On admission bilateral nasal packs were in situ, and there was no active bleeding. The patient was admitted for observation. On removal of the packs 48 hours later the bleeding recurred. A bedside rigid endoscopy performed to identify the cause of intractable epistaxis revealed a polypoidal mass filling the posterior half of the nasal cavity and extending into the middle meatus. An examination under general anaesthetic was therefore undertaken where the mass was biopsied and cautery applied to the bleeding surface. After a further 24 hour period of observation, the patient was discharged and a computed tomography (CT) scan of the sinuses arranged as an outpatient to assess the extent of the pathology.The initial biopsy results proved inconclusive with features of an organising thrombus. The CT scan revealed a completely opacified right maxillary antrum , with the antral disease being contiguous with further soft tissue thickening within the right nasal cavity and enveloping middle and inferior turbinates (Fig 1).
机译:简介:血管性鼻息肉是一种罕见且独特的炎性鼻窦息肉,可在临床和放射学上模拟鼻窦肿瘤。我们描述了一位80岁女士的血管扩张性鼻息肉的独特病例,该患者呈现复发性鼻出血和影像学特征,提示乳头状乳头状瘤倒置。根据怀疑是乳头状乳头状瘤倒置术,通过内镜下颌内侧内侧切除术进行了完全切除。最初,组织病理学被报道为炎性息肉,但后来被修改为血管扩张型鼻息肉。组织病理学发现:息肉明确,息肉具有间质退化性透明质改变,间质性出血和毛细血管扩张,表面扁平化的上皮被衬砌。结论:血管性鼻息肉是一种罕见的病理实体,因此可引起严重的诊断难题。因此,了解不同的临床表现和独特的组织病理学特征对于建立早期明确诊断很重要。此外,文献中很少有先例可以指导这种情况下的管理,因此,我们认为该报告在这方面值得关注和启发。引言血管性鼻息肉,也称为血管瘤性鼻息肉,很罕见,仅占所有炎性鼻窦息肉的5%。1实际上,迄今为止,文献中只报道了极少数。这些息肉以多种方式出现,通常模拟其他病理学,包括恶性肿瘤。我们以一名80岁的患者为例,该患者表现为单侧鼻腔肿块和鼻epi,其放射学结果最初提示为乳头状乳头状瘤倒置,但其组织病理学发现随后揭示了鼻腔息肉。病例报告一名80岁的女士因复发性鼻axis病史达5周,就诊于急症室(A&E)。在出现发作期间不能通过保守措施控制出血导致被指诊的耳鼻喉科前鼻填塞。她的合并症包括可以通过抗高血压药很好地控制的高血压以及以前服用过阿司匹林的短暂性脑缺血发作。入院时双侧鼻腔就位,没有活动性出血。该患者被允许观察。取出包装后48小时,出血再次发生。进行床旁硬性内窥镜检查以查明顽固性鼻axis的原因,发现在鼻腔后半部充满了息肉样肿块,并延伸至中耳道。因此,在全身麻醉下进行检查,对肿块进行活检并将烧灼术涂在出血表面。再经过24小时的观察后,患者出院,并安排了CT扫描作为门诊患者的鼻窦以评估病理学范围。初步的活检结果证明与血栓的组织特征无关。 CT扫描显示右上颌窦完全不透明,与肛门疾病相邻,右鼻腔内软组织进一步增厚,并包绕中鼻甲和下鼻甲(图1)。

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