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Comparison Of Fine Needle Aspiration Cytology Of Axillary Lymph Node And Biopsy In Breast Cancer Patients

机译:乳腺癌患者腋窝淋巴结细针穿刺细胞学检查及活检的比较

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PurposeAll the patients with a non-operative diagnosis of invasive breast cancer should have ipsilateral axillary ultrasound performed,preferably at the time of initial assessment. If this was not performed initially, it should be done as soon as possible followingcore biopsy diagnosis of the breast cancer. The number and morphology of any abnormal nodes should be documented1. Nonational guidelines are available to give the utility of FNA versus biopsy of axillary nodes. They are regarded as equal, however,we had a couple of difficult experiences in reporting of FNA results, and therefore we decided to do an audit while comparingthe two techniques by keeping the histology as gold standard.MethodThe specimens were searched from last two-year period starting from 1st January 2015 to 31 December 2016. All of the axillarylymph node FNA’s were searched through Winpath search engine. Only the axillary lymph nodes with breast cancers wereseparated. Out of these all the FNA’s which had no follow up histology were excluded. So, in the end 82 FNA specimens wereincluded in the audit. L codes for fine needle aspiration cytology were used (LC1 to LC5).Results82 FNAs were recorded. Fine needle aspiration cytology showed accuracy of 76.3%ConclusionOur LC3 and LC4 calling is relatively lower when compared with other centres. However, a little more consideration is neededregarding overcalling LC3. Despite the comparable results FNA has its limitations regarding sampling of the correct nodeshence the PPV of LC2 being 17%. There is a significant rate of LC1 which is dependent on performer’s competency amongothers.
机译:目的所有非手术诊断为浸润性乳腺癌的患者均应进行同侧腋窝超声检查,最好在初次评估时进行。如果最初没有执行此操作,则应在乳腺癌的核心活检诊断后尽快进行。任何异常结的数目和形态都应记录在案1。没有国家指南可提供FNA与腋窝淋巴结活检的实用性。他们被认为是平等的,但是,在报告FNA结果时我们遇到了一些困难的经验,因此我们决定在将两种技术进行比较的同时,将组织学作为黄金标准进行审核。方法从最近两年的标本中进行搜索从2015年1月1日到2016年12月31日这一时期。所有的腋窝淋巴结FNA都通过Winpath搜索引擎进行了搜索。仅分离出患有乳腺癌的腋窝淋巴结。在所有这些没有随访组织学的FNA中,将其排除在外。因此,最终在审核中包括了82个FNA标本。使用用于细针穿刺细胞学检查的L代码(LC1至LC5)。结果记录了82个FNA。细针穿刺细胞学检查的准确性为76.3%。结论与其他中心相比,我们的LC3和LC4呼叫率相对较低。但是,关于取消LC3,还需要更多考虑。尽管结果可比,但FNA在采样正确节点方面有其局限性,因此LC2的PPV为17%。 LC1的比率很高,这取决于表演者之间的能力。

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