Study Of Adnexal Tumors Of The Skin: A Three Year Study Of 25 Cases

摘要

Adnexal tumors of skin are uncommon in routine practice and they usually cause diagnostic problems. This study was undertaken with the aim of determining the incidence of adnexal tumors of skin in our department and to study detail histopathological character of each tumor by light microscopy. A prospective study was conducted for three years period from year 2004 to 2006 in department of pathology, Government Medical College, Baroda. During this study, we observed that incidence of Adnexal tumors of Skin was very low as compared to total burden of surgical specimen received (<0.5). Most of the tumors were found to be benign. (96%) Incidence of malignancy was low (04%). Tumors were observed more common in females as compared to males. Most of tumors were localized to head & Neck region (64%). Tumors involving pilosebaceous unit (40%) and sweat glands with eccrine differentiation were common (40%). Incidence of tumor with apocrine differentiation was low (08%). Introduction There are literally hundreds of neoplasms that can arise from cutaneous appendages and they are known since long. They are basically classified into four groups, tumors with differentiation towards hairs follicles, sebaceous glands, eccrine or apocrine sweat glands.(1,2) Most of tumors are benign and remain localized to site. Certain appendageal tumors have got importance because they behave as marker for internal visceral malignancy as in case of multiple trichilemomma, which act as marker for breast malignancy. Association between them is called cowden’s disease. (3) Appendageal tumors are clinically non-descript, flesh colored, solitary or multiple papules or nodule. Some of them found to have predilection for certain parts of body like eccrine poroma which is most common is lower limb, but can occur in other parts also.(4) The large majority of adnexal tumors of skin differentiate along only one line and this result in formation of reasonably distinctive types whose structure, cytochemistry and immunohistochemistry can be correlated with those of corresponding adnexa. However, since all cutaneous adnexa share same origin, so it is not surprising that the tumor arising from them may have many features in common. (5) Materials and Methods Materials for present study of 25 cases of skin adnexal tumors comes from patient admitted or attended O.P.D. during period 2004 to 2006 at S.S.G. Hospital, Baroda.Detailed microscopic examination was carried out. For histological examination, 10% formalin fixed embedded representative tissue sections were stained with Hematoxylin and Eosin. Where necessary, relevant sections were stained with PAS and final confirmation of the diagnosis was done.The details of clinical history and relevant investigation were obtained in every case and analyzed. Observations & Results A total of 25 Neoplasm of Skin Appendages were diagnosed during period of 2004 to 2006 in our department at S.S.G. Hospital, Baroda.Incidence of skin adnexal tumors as compared to total surgical pathological specimen we received found to be less than 0.5%.Following Table No. 1 shows the Male and Female Ratio observed in Adnexal tumors.