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Obstetrical and perinatal outcome in pregnant women with extrapulmonary tuberculosis

机译:肺外结核孕妇的产科和围产期结局

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Tuberculosis (TB) is a major health problem and a leading cause of illness and death from infectious disease. Tuberculosis in pregnancy has been associated with increased risks of prematurity and small for gestational age (SGA)infants.The present study is aimed to examine obstetrical and perinatal outcomes among women who had extra-pulmonary tuberculosis. Material and methods It was retrospective study involving patient who presented with extra pulmonary tuberculosis over a period of ten years (2008–2017)was reviewed. Diagnosed women were compared with controls in the ratio of six controls for each case. Data included age, parity and complications in the antenatal, intrapartum and postpartum periods. The mean birth weights of infant and the frequency of small for gestation age, neonatal depression and still births were used for perinatal outcome. Results During the period of study 30 pregnant women were booked for extra –pulmonary TB. 22/30(73.3%) were diagnosed having extra pulmonary -TB prior to pregnancy and were taking ATT (anti-tubercular therapy) during the pregnancy, in 8/30(26.6%) it was diagnosed during pregnancy. Age, parity were similar in two groups. There was significantly increased incidence of oligoamnios and preterm rupture of membrane (P?=?0.001). Mean gestation age of delivery in TB cases was 36.15?±?1.8 weeks as compared to37.5?±?0.5 weeks in low risk patients (P?=?0.001). The mean birth weight of the infants of mother with extra pulmonary TB was 2324.26?±?379.5 grams and 2712.3?±?635.7 for control group(P?=?0.001). Conclusion This study emphasize on the need for early diagnosis and treatment of tuberculosis preferably before pregnancy, regular medical follow up and good perinatal care.
机译:结核病(TB)是主要的健康问题,也是传染病致死的主要原因。怀孕期间的结核病与早产风险增加以及胎龄(SGA)婴儿的风险较小有关。本研究旨在检查患有肺外结核病妇女的产科和围产期结局。材料和方法回顾性研究,回顾了十年(2008-2017)期间出现肺结核的患者。将诊断出的女性与对照组的比例为每例六个对照组。数据包括产前,产中和产后的年龄,胎次和并发症。围产期结局采用婴儿的平均出生体重和胎龄,新生儿抑郁和死胎的频率。结果在研究期间,有30名孕妇接受了额外的肺结核预订。 22/30(73.3%)被诊断为在怀孕前有额外的肺结核,并且在怀孕期间正在接受ATT(抗结核治疗),在8/30(26.6%)的被诊断为怀孕期间。两组的年龄,平价相似。羊水过少和胎膜早破的发生率显着增加(P = 0.001)。结核病患者的平均分娩年龄为36.15±1.8周,而低危患者为37.5±0.5周(P = 0.001)。母亲患有肺结核的婴儿的平均出生体重为2324.26?±?379.5克,对照组为2712.3?±?635.7(P?=?0.001)。结论本研究强调需要早期诊断和治疗结核病,最好在怀孕前,定期的医疗随访和良好的围产期护理。

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