Plasmonic Biosensors on a Chip for Point-of-Care Applications' name='citation_title

摘要

Plasmonic biosensors have emerged as one of the most suitable sensors for future cost-effective clinical analysis and point-of-care platforms. They are based on the plasmonic properties of gold nanoparticles and nanostructures, principally, on the sensitivity of the gold plasmon band to any change in the surrounding environment. The successful development of plasmonic biosensors are the result of the progress in nanotechnology and microfabrication and the next step, their integration in a lab-on-a-chip, allows their miniaturization and portability. Miniaturized devices will find their way to clinics and patient's bedside as well as to remote places and developing countries, improving healthcare for everybody. In this paper, in the beginning, a short introduction on the phenomenon of plasmonics, the basic configurations of the instruments, and approaches for sensing are provided. Then, the advantages stemming from the integration of plasmonic biosensors into a microfluidic device are emphasized. The end product of a successful integration and miniaturization process is a high-performance, point-of-care device with benefits to healthcare and personalized medicine.