A 35-year-old woman was referred to our institution at 19 weeks' gestation because a mass located at the right fetal thigh was noted, reporting with a 46,XX karyotype of cultured amniotic cells. Prenatal ultrasound examinations revealed a 73 mm × 47 mm × 35 mm irregular multiseptated cystic mass involving the whole right fetal thigh with no obvious blood flow visualized using color Doppler images (Fig. 1A and B). The remaining ultrasound images for the female fetus, placenta, and amniotic fluid were unremarkable. Given a tentative diagnosis of lymphangioma and uncertain postnatal prognosis regarding functional and aesthetic impairments after treatment, the patient made a decision to terminate the pregnancy. Postmortem photographs were compatible with the prenatal three-dimensional ultrasound images (Fig. 2A and B). The pathologic reports confirmed an isolated unencapsulated cavernous lymphangioma involving the dermis and subcutaneous layers and composed of multiple dilated thin-wall lymphatic vessels filled with proteinaceous fluid (Fig. 3).
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