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Evaluation of Coronary Artery–Saphenous Vein Composite Grafts: The Aortic No-Touch Technique

机译:冠状动脉-大隐静脉复合移植物的评估:主动脉非接触技术

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We retrospectively compared the results of conventional coronary artery bypass grafting (CABG) performed on patients who showed no preoperative evidence of serious atherosclerosis of the ascending aorta with the results of the aortic no-touch technique (using coronary artery–saphenous vein composite grafts) on CABG patients who did show such evidence. From 2003 through 2012, 3,152 consecutive patients underwent isolated primary CABG at our hospital. We chose 360 for the current study. The study group (n=120) comprised patients who had undergone operation via the aortic no-touch technique. Propensity-score-matching (1:2) was used to select the control group of 240 patients who had undergone conventional CABG. Early and late survival rates, reintervention-free survival rates, and freedom from cardiac death were compared. Early and late mortality rates were similar in the study and control groups ( P =0.19 vs P =0.29, respectively), as were cardiac-related death (2.5% vs 2.1%, respectively; P =0.53) and overall death (8.3% vs 7.9%, respectively; P =0.51). Overall survival rates were 91.7% vs 92.1% and freedom-from-cardiac-death rates were 97.4% vs 97.5% ( P =0.71 vs P =0.78, respectively; mean follow-up period, 5.27 ± 2.51 yr). Reintervention-free survival rates were also similar (96.7% vs 98.8%, respectively; P =0.2). As a result of the similar rates of early and late survival, reintervention-free survival, and freedom from cardiac death, we conclude that the aortic no-touch technique with composite grafts might be a reasonable option in patients who have atherosclerotic ascending aorta that cannot be clamped.
机译:我们回顾性地比较了没有术前证据表明升主动脉严重动脉粥样硬化的患者的常规冠状动脉旁路移植术(CABG)的结果与无动脉接触技术(使用冠状动脉-大隐静脉复合移植物)的结果。确实有此类证据的CABG患者。从2003年到2012年,我院连续3152例患者接受了孤立的原发性CABG治疗。我们为当前研究选择了360。研究组(n = 120)包括通过主动脉非接触技术进行手术的患者。倾向得分匹配(1:2)用于选择240例接受常规CABG的患者作为对照组。比较早期和晚期生存率,无再干预生存率和免于心脏死亡。研究组和对照组的早期和晚期死亡率相似(分别为P = 0.19 vs P = 0.29),与心脏相关的死亡率(分别为2.5%vs 2.1%; P = 0.53)和总体死亡率(8.3%)相似。分别为7.9%; P = 0.51)。总生存率分别为91.7%和92.1%,而无心死的死亡率分别为97.4%和97.5%(分别为P = 0.71和P = 0.78;平均随访时间为5.27±2.51年)。无再干预生存率也相似(分别为96.7%和98.8%; P = 0.2)。由于早期和晚期生存率,无再干预生存率和无心源性死亡的发生率相似,我们得出的结论是,对于没有动脉粥样硬化升主动脉的患者,复合材料主动脉无接触技术可能是一个合理的选择。被夹紧。

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