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Maternal serum uric acid and calcium as predictors of hypertensive disorder of pregnancy: A case control study

机译:孕妇血清尿酸和钙可预测妊娠高血压疾病:病例对照研究

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ObjectivesCompare serum uric acid and calcium levels among normotensive and hypertensive pregnant women, to compare maternal and perinatal outcomes in two groups.Materials and methodsProspective case control study was conducted after ethical approval in Obstetrics and Gynaecology department of rural tertiary care centre of Northern India, over seven months. Total 220 antenatal women ≥34 weeks of gestation with 110 cases having hypertensive disorder of pregnancy and 110 controls with normal blood pressure were compared for maternal uric acid and calcium levels and maternal, perinatal outcomes.ResultsMean?±?SD values of uric acid and calcium in control group was 4.42?±?1.42?mg/dl and 8.94?±?0.6?mg/dl, whereas in cases they were 6.8?±?2.72?mg/dl and 8.61?±?0.78?mg/dl (p?
机译:目的比较正常血压和高血压孕妇的血清尿酸和钙水平,以比较两组的母亲和围产期结局。材料和方法在获得伦理学批准后,在印度北部农村三级医疗中心妇产科进行了前瞻性病例对照研究。七个月。比较220例≥34周妊娠的产前妇女,110例妊娠高血压疾病和110例血压正常的孕妇的孕妇尿酸和钙水平以及孕妇,围产期结局。结果尿酸和钙的平均值±SD值对照组为4.42±1.42mg / dl和8.94±0.62mg / dl,而对照组为6.8±2.72mg / dl和8.61±0.78μg/ dl(p <0.05。在高血压病例中,最常见的分娩方式是诱导分娩,然后进行下段剖腹产,而在对照组中,多数分娩是自发的,并且是阴道分娩的(p <0.05)。与对照组相比,具有较高尿酸和较低钙的高血压妇女围生期结局不良(p <0.05)。对照组新生儿出生体重的平均值±SD为2.81±0.295Kg,病例为2.56±0.421Kg。高血压妇女的新生儿出生体重与母体尿酸显着相关,而不是钙。与对照组相比,高尿酸​​血症和低钙水平的患者的总体预后不良。结论与健康的正常血压女性相比,妊娠高血压疾病的孕妇的高尿酸血症和低钙血症与孕妇,围产期不良预后相关。

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