Influence of the imaging method and histopathological features on preoperative size prediction of ductal carcinoma in situ (DCIS) of the breast

摘要

Aim of the?study: The?aim of the?study was to evaluate the?accuracy of mammography and ultrasonography in predicting preoperative DCIS size compared to final histopathologic measurement of the?extent of DCIS. Material and methods: A?retrospective analysis was performed of the?clinical, histopathological and imaging records of 32 consecutive female patients initially treated by breast-conserving surgery for DCIS between 1999 and 2005. Group 1 consisted of 19 female patients with a?palpable breast tumor, while group 2 comprised 13 female individuals with no palpable breast lesion. All patients were preoperatively diagnosed with biopsy. Results: In group 1, mammography size was smaller than histopathological size in 14 patients (73.68%), while they were equal in 5 cases (26.31%). However, in group 2, mammography size was the?same as histopathological size in 5 cases (38.46%), but was smaller in 8 individuals (61.53%). The?degree of the?underestimations for both imaging methods compared to pathological size were identical, with a?value of 1.1 ±0.9 cm and 1.2 ±1.1 cm for groups 1 and 2, respectively. Furthermore, in both study groups, as final histopathologic size decreased, the?degree of underestimation increased (p Conclusions: The?present study demonstrates that smaller DCIS pathological size is associated with greater discrepancies in imaging method size prediction.