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Mitigating transmit B 1 inhomogeneity in the liver at 7T using multispoke parallel transmit RF pulse design

机译:使用多辐并行发射RF脉冲设计缓解7T时肝脏中的发射B 1不均匀性

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In this work, the use of multi-spoke slice-selective parallel transmit (pTX) RF pulse was explored to address B1+ inhomogeneity in the largest transverse section of the liver at 7T. The impact of the number of spokes was specifically investigated, considering RF pulses consisting of 2, 3 and 4 spokes, as well as single-spoke RF pulses corresponding to static B1 shimming. Healthy volunteers were imaged on a whole body MR scanner equipped with an eight-channel transmit system. A robust and fast transmit B1 (B1+) estimation method was employed to obtain the eight-channel B1+ maps within a single breath hold. Gradient echo (GRE) images of the liver were acquired using the four different RF pulses and the results were compared. The use of static B1 shimming (i.e., 1-spoke RF pulse) resulted in partial improvement but significant signal dropouts were still observed in the target region. By comparison, the use of multi-spoke pTX RF pulse design gave rise to much improved excitation homogeneity without signal dropouts. These results demonstrate the effectiveness of multi-spoke pTX RF pulse design in B1+ homogenization for liver magnetic resonance imaging (MRI) at 7T. The current findings at 7T may have implications for body imaging applications in clinical settings at 3T where B1+ inhomogeneities are also known for degrading image quality in the torso.
机译:在这项工作中,探索了使用多辐条切片选择性并行发射(pTX)RF脉冲来解决肝脏最大横切面中的 B 1 +不均匀性在7时。专门研究了辐条数量的影响,考虑了由2、3和4个辐条组成的RF脉冲以及对应于静态 B 1 的单辐RF脉冲匀称。健康志愿者在配有八通道传输系统的全身MR扫描仪上成像。采用鲁棒且快速传输的 B 1 B 1 +)估计方法获得八通道 B 1 +会在一次屏住呼吸时映射。使用四个不同的RF脉冲获取肝脏的梯度回波(GRE)图像,并对结果进行比较。静态 B 1 匀场(即1辐RF脉冲)的使用导致部分改善,但在目标区域仍观察到明显的信号丢失。相比之下,多辐pTX RF脉冲设计的使用大大提高了激励均匀性,而没有信号丢失。这些结果证明了在 B 1 +均质化中多辐照pTX RF脉冲设计在7T时进行肝脏磁共振成像(MRI)的有效性。 7T的当前发现可能对3T临床环境中的身体成像应用有影响,其中 B 1 +不均匀性也被认为会降低躯干的图像质量。

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