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Locomotion, cognition and influences of nutrition in ageing

机译:营养对衰老的运动,认知和影响

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摘要

Gait and cognitive impairments in older adults can reflect the simultaneous existence of two syndromes that affect certain brain substrates and pathologies. Nutritional deficiencies, which are extremely common among elderly population worldwide, have potential to impact the existence and rehabilitation of both syndromes. Gait and cognition are controlled by brain circuits which are vulnerable to multiple age-related pathologies such as vascular diseases, inflammation and dementias that may be caused or accentuated by poor nutrition or deficiencies that lead to cognitive, gait or combined cognitive and gait impairments. The following review aims to link gait and cognitive classifications and provide an overview of the potential impact of nutritional deficiencies on both neurological and gait dysfunctions. The identification of common modifiable risk factors, such as poor nutrition, may serve as an important preventative strategy to reduce cognitive and mobility impairments and moderate the growing burden of dementia and disability worldwide.
机译:老年人的步态和认知障碍可反映出两种综合症的同时存在,这些综合症影响某些大脑的底物和病理。营养不足在全世界老年人群中极为普遍,有可能影响这两种综合症的存在和康复。步态和认知受到大脑回路的控制,大脑回路易受多种与年龄相关的疾病的影响,例如血管疾病,炎症和痴呆,这些疾病可能是由于营养不良或缺乏导致认知,步态或认知和步态综合障碍而引起或加重的。以下综述旨在将步态和认知分类联系起来,并概述营养不足对神经系统和步态功能障碍的潜在影响。确定常见的可改变的危险因素,例如营养不良,可以作为重要的预防策略,以减少认知和活动能力障碍,并减轻全球范围内痴呆和残疾日益加重的负担。

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