IL-27 Signaling Is Crucial for Survival of Mice Infected with African Trypanosomes via Preventing Lethal Effects of CD4+ T Cells and IFN-γ

Donglei Sun; Gongguan Liu; Hui Wu; Jinjun Xu; Meiqing Shi; Stefan Magez; Xiaoping Zhu; Xiquan Zhang

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IL-27 Signaling Is Crucial for Survival of Mice Infected with African Trypanosomes via Preventing Lethal Effects of CD4+ T Cells and IFN-γ

机译：IL-27信号通过预防CD4 + T细胞和IFN-γ的致死作用对于非洲锥虫感染的小鼠的生存至关重要。

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《PLoS Pathogens 》 |2015年第7期| 共页
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Donglei Sun; Gongguan Liu; Hui Wu; Jinjun Xu; Meiqing Shi; Stefan Magez; Xiaoping Zhu; Xiquan Zhang;
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1. IL-27 Signaling Is Crucial for Survival of Mice Infected with African Trypanosomes via Preventing Lethal Effects of CD4+ T Cells and IFN-γ [J] . Donglei Sun, Gongguan Liu, Hui Wu, PLoS Pathogens . 2015 ,第7期

机译：IL-27信号通过预防CD4 + T细胞和IFN-γ的致死作用对于非洲锥虫感染的小鼠的生存至关重要。
2. Blockade of IL-27 signaling ameliorates herpes stromal keratitis with upregulated CD4+ Foxp3+ regulatory T cells influx in mice [J] . Likun Xia, Tianchang Tan, Yang Li, Indian Journal of Ophthalmology . 2019 ,第11期

机译：上调CD4 + Foxp3 +调节性T细胞流入小鼠后，IL-27信号传导的阻断可改善疱疹基质性角膜炎
3. Experimental African Trypanosomiasis: A Subset of Pathogenic, IFN-{gamma}-Producing, MHC Class II-Restricted CD4+ T Cells Mediates Early Mortality in Highly Susceptible Mice. [J] . Shi M, Wei G, Pan W, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2006 ,第3期

机译：实验性非洲锥虫病：致病性，产生IFN-γ的MHC II类限制性CD4 + T细胞的亚集介导了高度易感性小鼠的早期死亡率。
4. Effects of HIV-1 Proteins on the Fas-Mediated Apoptotic Signaling Cascade: A Computational Study of Latent CD4+ T Cell Activation [C] . John Jack, Andrei Paun, Alfonso Rodriguez-Paton International Workshop on Membrane Computing . 2009

机译：HIV-1蛋白对Fas介导的凋亡信号级联的影响：潜在CD4 + T细胞活化的计算研究
5. The Exploration of an Effective Medical Countermeasure Enhancing Survival and Hematopoietic Recovery and Preventing Immune Insufficiency in Lethally-Irradiated Mice [D] . ?Wu, Tong 2020

机译：一个有效的医疗对策增强生存与造血恢复和预防免疫不全致死剂量辐照小鼠中的探索
6. IL-27 Signaling Is Crucial for Survival of Mice Infected with African Trypanosomes via Preventing Lethal Effects of CD4+ T Cells and IFN-γ [O] . Gongguan Liu, Jinjun Xu, Hui Wu, 2012

机译：IL-27信号通过预防CD4 + T细胞和IFN-γ的致死作用对于非洲锥虫感染的小鼠的生存至关重要。
7. IL-27 Signaling Is Crucial for Survival of Mice Infected with African Trypanosomes via Preventing Lethal Effects of CD4+ T Cells and IFN-γ. [O] . Gongguan Liu, Jinjun Xu, Hui Wu, 2015

机译：通过预防CD4 + T细胞和IFN-γ的致死作用，IL-27信号传导对于感染非洲锥虫的小鼠的存活至关重要。

IL-27 Signaling Is Crucial for Survival of Mice Infected with African Trypanosomes via Preventing Lethal Effects of CD4+ T Cells and IFN-γ

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