Sodium Stibogluconate (SSG) & Paromomycin Combination Compared to SSG for Visceral Leishmaniasis in East Africa: A Randomised Controlled Trial

Ahmed Musa; Eltahir Khalil; Asrat Hailu; Joseph Olobo; Manica Balasegaram; Raymond Omollo; Tansy Edwards; Juma Rashid; Jane Mbui; Brima Musa; Abuzaid Abdalla Abuzaid; Osama Ahmed; Ahmed Fadlalla; Ahmed El-Hassan; Marius Mueller; Geoffrey Mucee; Simon Njoroge; Veronica Manduku; Geoffrey Mutuma; Lilian Apadet; Hudson Lodenyo; Dedan Mutea; George Kirigi; Sisay Yifru; Getahun Mengistu; Zewdu Hurissa; Workagegnehu Hailu; Teklu Weldegebreal; Hailemariam Tafes; Yalemtsehay Mekonnen; Eyasu Makonnen; Serah Ndegwa; Patrick Sagaki; Robert Kimutai; Josephine Kesusu; Rhoda Owiti; Sally Ellis; Monique Wasunna

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Sodium Stibogluconate (SSG) & Paromomycin Combination Compared to SSG for Visceral Leishmaniasis in East Africa: A Randomised Controlled Trial

机译：替加葡糖酸钠（SSG）和巴龙霉素联合应用SSG治疗东非内脏利什曼病：一项随机对照试验

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Background Alternative treatments for visceral leishmaniasis (VL) are required in East Africa. Paromomycin sulphate (PM) has been shown to be efficacious for VL treatment in India.

机译：背景技术东非地区需要内脏利什曼病（VL）的替代疗法。在印度，硫酸巴龙霉素（PM）已证明对VL治疗有效。

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《PLOS Neglected Tropical Diseases》 |2012年第6期|共10页
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Ahmed Musa; Eltahir Khalil; Asrat Hailu; Joseph Olobo; Manica Balasegaram; Raymond Omollo; Tansy Edwards; Juma Rashid; Jane Mbui; Brima Musa; Abuzaid Abdalla Abuzaid; Osama Ahmed; Ahmed Fadlalla; Ahmed El-Hassan; Marius Mueller; Geoffrey Mucee; Simon Njoroge; Veronica Manduku; Geoffrey Mutuma; Lilian Apadet; Hudson Lodenyo; Dedan Mutea; George Kirigi; Sisay Yifru; Getahun Mengistu; Zewdu Hurissa; Workagegnehu Hailu; Teklu Weldegebreal; Hailemariam Tafes; Yalemtsehay Mekonnen; Eyasu Makonnen; Serah Ndegwa; Patrick Sagaki; Robert Kimutai; Josephine Kesusu; Rhoda Owiti; Sally Ellis; Monique Wasunna;
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1. Safety and Efficacy of miltefosine alone and in combination with sodium stibogluconate and liposomal amphotericin B for the treatment of primary visceral leishmaniasis in East Africa: study protocol for a randomized controlled trial [J] . Raymond Omollo, Neal Alexander, Tansy Edwards, Trials . 2011,第1期

机译：单用米非磷碱以及与stibogluconate钠和脂质体两性霉素B组合治疗东非原发性内脏利什曼病的安全性和有效性：一项随机对照试验的研究方案
2. A prospective randomized, comparative, open-label trial of the safety and efficacy of paromomycin (aminosidine) plus sodium stibogluconate versus sodium stibogluconate alone for the treatment of visceral leishmaniasis. [J] . Thakur CP, Kanyok TP, Pandey AK, Transactions of the Royal Society of Tropical Medicine and Hygiene . 2000,第4期

机译：帕罗霉素（氨基嘧啶）加司他葡糖酸钠与单独司他葡糖酸钠治疗内脏利什曼病的安全性和有效性的前瞻性随机对照开放性试验。
3. The Pharmacodynamic Interactions of Sodium Stibogluconate (SSG) and Paromomycin (PM) on Various Isolated Tissues Preparations [J] . M.M.E. Mudawi, Sania A.I. Shaddad, I.B. Eltayeb, Research Journal of Pharmacology . 2009,第2期

机译：糖基葡萄糖酸钠（SSG）和巴龙霉素（PM）对各种离体组织制剂的药效相互作用
4. The early external cephalic version (ECV) trial: A randomised controlled trial of ECV beginning at between 34--36 weeks compared to 37--38 weeks gestation. [D] . Hutton, Eileen Katherine McNally. 2003

机译：早期体外头颅试验（ECV）：一项ECV随机对照试验始于妊娠34--36周，而妊娠37--38周。
5. Sodium Stibogluconate (SSG) Paromomycin Combination Compared to SSG for Visceral Leishmaniasis in East Africa: A Randomised Controlled Trial [O] . Ahmed Musa, Eltahir Khalil, Asrat Hailu, 2012

机译：替加葡糖酸钠（SSG）和巴龙霉素联合SSG治疗东非内脏利什曼病：一项随机对照试验。
6. Sodium Stibogluconate (SSG) & Paromomycin Combination Compared to SSG for Visceral Leishmaniasis in East Africa: A Randomised Controlled Trial [O] . Musa, Ahmed, Khalil, Eltahir, Hailu, Asrat, 2012

机译：替加葡糖酸钠（SSG）和巴龙霉素联合SSG治疗东非内脏利什曼病：一项随机对照试验。
7. Placebo-Controlled Clinical Trial of Sodium Stibogluconate (Pentostam) vs.Ketoconazole for Treating Cutaneous Leishmaniasis in Guatemala [R] . Navin, T. R. 1991

机译：葡萄糖酸钠（pentostam）与酮康唑治疗危地马拉皮肤利什曼病的安慰剂对照临床试验

Sodium Stibogluconate (SSG) & Paromomycin Combination Compared to SSG for Visceral Leishmaniasis in East Africa: A Randomised Controlled Trial

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