Randomised Controlled Double-Blind Non-Inferiority Trial of Two Antivenoms for Saw-Scaled or Carpet Viper (Echis ocellatus) Envenoming in Nigeria

Isa S. Abubakar; Saidu B. Abubakar; Abdulrazaq G. Habib; Abdulsalam Nasidi; Nandul Durfa; Peter O. Yusuf; Solomon Larnyang; John Garnvwa; Elijah Sokomba; Lateef Salako; R. David G Theakston; Ed Juszczak; Nicola Alder; David A. Warrell; for the Nigeria-UK EchiTab Study Group

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Randomised Controlled Double-Blind Non-Inferiority Trial of Two Antivenoms for Saw-Scaled or Carpet Viper (Echis ocellatus) Envenoming in Nigeria

机译：尼日利亚针对锯切规模或地毯毒蛇（Echis ocellatus）毒液的两种抗毒液的随机对照双盲非劣效性试验

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Background In West Africa, envenoming by saw-scaled or carpet vipers (Echis ocellatus) causes great morbidity and mortality, but there is a crisis in supply of effective and affordable antivenom (ISRCTN01257358).

机译：背景技术在西非，锯屑或地毯carpet蛇（棘皮E蛇）引起的致病和致死率很高，但有效且负担得起的抗蛇毒血清供应存在危机（ISRCTN01257358）。

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《PLOS Neglected Tropical Diseases》 |2010年第7期|共10页
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Isa S. Abubakar; Saidu B. Abubakar; Abdulrazaq G. Habib; Abdulsalam Nasidi; Nandul Durfa; Peter O. Yusuf; Solomon Larnyang; John Garnvwa; Elijah Sokomba; Lateef Salako; R. David G Theakston; Ed Juszczak; Nicola Alder; David A. Warrell; for the Nigeria-UK EchiTab Study Group;
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1. Pre-clinical and preliminary dose-finding and safety studies to identify candidate antivenoms for treatment of envenoming by saw-scaled or carpet vipers (Echis ocellatus) in northern Nigeria. [J] . Abubakar S. B., Abubakar I. S., Habib A. G., Toxicon: An International Journal Devoted to the Exchange of Knowledge on the Poisons Derived from Animals, Plants and Microorganisms . 2010,第4期

机译：临床前和初步剂量寻找与安全性研究，以确定在尼日利亚北部用锯鳞或地毯蛇蝎（Echis ocellatus ）进行毒液治疗的候选抗蛇毒血清。
2. Formulation of a liquid ovine Fab-based antivenom for the treatment of envenomation by the Nigerian carpet viper (Echis ocellatus) [J] . Al-Abdulla I, Garnvwa JM, Rawat S, Toxicon: An International Journal Devoted to the Exchange of Knowledge on the Poisons Derived from Animals, Plants and Microorganisms . 2003,第4期

机译：配制基于液态绵羊Fab的抗蛇毒素，用于治疗尼日利亚地毯vi蛇（Echis ocellatus）的毒杀
3. Antivenom therapy of carpet viper (Echis ocellatus) envenoming: Effectiveness and strategies for delivery in West Africa [J] . Abdulrazaq G. Habib, David A. Warrell Toxicon: An International Journal Devoted to the Exchange of Knowledge on the Poisons Derived from Animals, Plants and Microorganisms . 2013,第Null期

机译：地毯蛇毒（Echis ocellatus）毒化的抗毒疗法：西非的有效性和策略
4. DEEP PROTEOMICS OF SAW-SCALED VIPER (ECHIS CARINATUS SOCHUREKI) VENOM BY INTEGRATED TOP-DOWN AND BOTTOM-UP MASS SPECTROMETRIC APPROACHES [C] . Parviz Ghezellou, Vannuruswamy Garikapati, Seyed Mahdi Kazemi, International Mass Spectrometry Conference . 2018

机译：通过集成的自上而下和自下而上的质谱方法，锯鳞蛇（Echis Carinatus Sochureki）的深蛋白质组学毒液
5. The early external cephalic version (ECV) trial: A randomised controlled trial of ECV beginning at between 34--36 weeks compared to 37--38 weeks gestation. [D] . Hutton, Eileen Katherine McNally. 2003

机译：早期体外头颅试验（ECV）：一项ECV随机对照试验始于妊娠34--36周，而妊娠37--38周。
6. Randomised Controlled Double-Blind Non-Inferiority Trial of Two Antivenoms for Saw-Scaled or Carpet Viper (Echis ocellatus) Envenoming in Nigeria [O] . Isa S. Abubakar, Saidu B. Abubakar, Abdulrazaq G. Habib, 2010

机译：尼日利亚针对锯切规模或地毯毒蛇（Echis ocellatus）毒液的两种抗毒液的随机对照双盲非劣效性试验
7. Randomised controlled double-blind non-inferiority trial of two antivenoms for saw-scaled or carpet viper (Echis ocellatus) envenoming in Nigeria. [O] . Abubakar, IS, Abubakar, SB, Habib, AG, 2010

机译：尼日利亚针对锯齿状或地毯蛇蝎（Echis ocellatus）毒液的两个抗蛇毒动物的随机对照双盲非劣效性试验。

Randomised Controlled Double-Blind Non-Inferiority Trial of Two Antivenoms for Saw-Scaled or Carpet Viper (Echis ocellatus) Envenoming in Nigeria

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