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Investigation of a Medieval Pilgrim Burial Excavated from the Leprosarium of St Mary Magdalen Winchester, UK

机译:英国圣玛丽·玛格达琳·温彻斯特(St Mary Magdalen Winchester)麻风病院出土的中世纪朝圣者墓葬的调查

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We have examined the remains of a Pilgrim burial from St Mary Magdalen, Winchester. The individual was a young adult male, aged around 18–25 years at the time of death. Radiocarbon dating showed the remains dated to the late 11th–early 12th centuries, a time when pilgrimages were at their height in Europe. Several lines of evidence in connection with the burial suggested this was an individual of some means and prestige. Although buried within the leprosarium cemetery, the skeleton showed only minimal skeletal evidence for leprosy, which was confined to the bones of the feet and legs. Nonetheless, molecular testing of several skeletal elements, including uninvolved bones all showed robust evidence of DNA from Mycobacterium leprae, consistent with the lepromatous or multibacillary form of the disease. We infer that in life, this individual almost certainly suffered with multiple soft tissue lesions. Genotyping of the M.leprae strain showed this belonged to the 2F lineage, today associated with cases from South-Central and Western Asia. During osteological examination it was noted that the cranium and facial features displayed atypical morphology for northern European populations. Subsequently, geochemical isotopic analyses carried out on tooth enamel indicated that this individual was indeed not local to the Winchester region, although it was not possible to be more specific about their geographic origin.
机译:我们检查了温彻斯特圣玛丽·玛格达琳的朝圣者遗体。该个体为年轻的成年男性,死亡时年龄约18-25岁。放射性碳测年表明,这些遗骸的年代可以追溯到11世纪末-12世纪初,当时朝圣在欧洲达到顶峰。与葬礼有关的几条证据表明,这是具有一定手段和声望的个人。尽管被埋葬在麻风病墓地中,但骨骼仅显示出最小的麻风骨骼证据,其仅限于脚和腿的骨骼。尽管如此,对包括未受累骨骼在内的几个骨骼成分的分子测试均显示出来自麻风分枝杆菌的DNA的有力证据,与该疾病的原发或多细菌形式相符。我们推断,在生活中,这个人几乎肯定会遭受多种软组织损伤。 Leprae菌株的基因分型显示这属于2F谱系,今天与中南亚和西亚的病例有关。在骨科检查过程中,注意到颅骨和面部特征显示出北欧人群的非典型形态。随后,对牙釉质进行的地球化学同位素分析表明,该人确实不是温彻斯特地区的本地人,尽管不可能对其地理起源更加具体。

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