Correction: The GATA Factor elt-1 Regulates C. elegans Developmental Timing by Promoting Expression of the let-7 Family MicroRNAs

摘要

There are errors in Table 1 . The trans-heterozygous genotypes under ‘ etl-1 genotype ’ are not displayed in the standard way; ku491 + should be ku491 /+, ok1002 + should be ok1002 /+ and ku491 ok1002 should be ku491 / ok1002 . The correct table is displayed underneath. 10.1371/journal.pgen.1005257.t001 Table 1 elt-1 mutants have an L4-stage bursting vulva and defective alae formation and elt-1(ku491) is a partial loss-of- function allele. Strain RNAi L4 Bursting Vulva L4 Molt Alae Young Adult Seam Cells % n Absent (%) Gapped (%) Present (%) n SCM Std Dev n wild-type Empty vector ~(a) 0.0 245 0.0 0.0 100.0 27 16.0 0.4 27 daf-12(rh61rh411) Empty vector ~(a) 0.0 183 0.0 0.0 100.0 24 18.1 1.6 24 elt-1(ku491) Empty vector ~(a) 3.6 169 88.4 3.8 7.6 26 12.9 2.2 15 elt-1(ku491);daf-12(rh61rh411) Empty vector ~(a) 55.1 198 88.8 0.0 11.1 18 39.7 9.8 29 wild-type elt-1 48.7 117 100.0 0.0 0.0 21 0.5 0.8 21 daf-12(rh61rh411) elt-1 56.7 90 90.0 5.0 5.0 20 0.2 0.4 20 elt-1(ku491) elt-1 76.3 114 100.0 0.0 0.0 27 1.3 1.2 27 elt-1(ku491);daf-12(rh61rh411) elt-1 94.8 231 96.4 3.6 0.0 28 2.0 2.2 28 elt-1 genotype ~(b) daf-12 genotype ku491/+ Wild-type 0.0 60 0.0 0.0 100.0 19 15.9 0.3 18 ku491/+ rh61rh411 0.0 57 0.0 0.0 100.0 18 18.3 1.8 18 ok1002/+ Wild-type 0.0 92 0.0 0.0 100.0 18 16.0 0.3 18 ok1002/+ rh61rh411 0.0 78 0.0 0.0 100.0 17 18.2 1.9 17 ku491/ok1002 Wild-type 1.9 52 84.0 16.0 0.0 25 9.4 ~(c) 2.0 25 ku491/ok1002 rh61rh411 65.9 41 100.0 0.0 0.0 20 18.2 ~(d) 6.6 20 ~(a)Phenotypes on empty-vector control RNAi were similar to the standard E . coli strain OP50. ~(b)An allele of elt-1(ku491) linked to mutations in unc-24 and dpy-20 was used for these strains. ~(c)For elt-1(ku491) animals vs elt-1(ku491)-over-elt-1(null) animals at the young adult stage, the p-value for the comparison of seam-cell numbers is 0.0340 ~(d)For elt-1(ku491);daf-12(rh61rh411) animals vs elt-1(ku491)-over-elt-1(null);daf-12(rh61rh411) animals at the young adult stage, the p-value for the comparison of seam-cell numbers is < 0.0001.