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首页> 外文期刊>Physiological Research >L-arginine in combination with sildenafil potentiates the attenuation of hypoxic pulmonary hypertension in rats.
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L-arginine in combination with sildenafil potentiates the attenuation of hypoxic pulmonary hypertension in rats.

机译:L-精氨酸联合西地那非可增强大鼠低氧性肺动脉高压的减轻。

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Chronic hypoxia induces an increased production of nitric oxide (NO) in pulmonary prealveolar arterioles. Bioavailability of the NO in the pulmonary vessels correlates with concentration of L- arginine as well as activity of phosphodiesterase-5 enzyme (PD
机译:慢性缺氧会导致肺泡前小动脉中一氧化氮(NO)的产生增加。肺血管中NO的生物利用度与L-精氨酸的浓度以及磷酸二酯酶5酶(PD

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