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Assessment of viscoelasticity and hydration effect of herbal moisturizers using bioengineering techniques

机译:使用生物工程技术评估草药保湿剂的粘弹性和保湿作用

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Background:A number of moisturizers are available containing natural hydrating, moisturizing, fi rming and occlusive property-imparting agent in the form of herbal extracts, juice and oils. The aim of this study is to assess the hydration and viscoelastic effect of commercially available herbal moisturizers, containing different herbs, on human skin, after a single and 3-week period of application using skin bio mechanical and electrical techniques.Materials and Methods:Twenty selected herbal moisturizers (HM) were coded as HM1-HM20. Forty volunteers, mean age of 40 ± 9 years, were participated in the short- and long-term study. Skin properties in terms of hydration and viscoelastic parameters were measured by multitester and cutometer, respectively. Measurements were done before and after 1, 2, and 3 h (single application) and for the 3-week period of daily application.Results:After single application, significant increase has been observed in both the skin electrical (P < 0.001) and mechanical properties (P < 0.01) as compared to the control, at which no products were applied. After the 3-week period, both effects are maintained and found to be significant at P < 0.001. Short-and long-term study revealed that out of 20 herbal moisturizers, HM8 and HM10 show pronounced increase in skin hydration (90-100%) and HM8, HM10, and HM11 shown marked increase in skin viscoelasticity (90-95%).Conclsuion:The possible reason of maximum effects obtained by these products is multifunctional effects of active ingredients of incorporated herbs. Combined used of both non invasive techniques is useful to substantiate the hydrating and viscoelasticity claim of herbal moisturizer. Short- and long-terms study revealed the best performing herbal moisturizer.
机译:背景:许多保湿剂都以草药提取物,果汁和油的形式包含天然保湿,保湿,定型和闭塞性赋予特性的保湿剂。这项研究的目的是使用皮肤生物机械和电气技术,在施用了一个星期和三个星期后,评估含有不同草药的市售草药保湿剂对人体皮肤的保湿和粘弹性作用。材料和方法:二十选定的草药保湿剂(HM)编码为HM1-HM20。 40名平均年龄为40±9岁的志愿者参加了短期和长期研究。分别通过万用表和角质仪测量皮肤的水合作用和粘弹性参数。在1、2、3 h(单次使用)之前和之后以及每天使用的三周期间进行测量。结果:单次使用后,皮肤电性和P值均显着增加(P <0.001)。与未施加产品的对照相比,机械性能(P <0.01)。在3周的时间后,两种作用均得以维持,并在P <0.001时显着。短期和长期研究表明,在20种草药保湿剂中,HM8和HM10显着增加皮肤水合作用(90-100%),HM8,HM10和HM11显着增加皮肤粘弹性(90-95%)。结论:这些产品获得最大功效的可能原因是所掺入草药有效成分的多功能功效。两种非侵入性技术的组合使用可用于证实草药保湿剂的保湿和粘弹性要求。短期和长期研究表明,效果最佳的草药保湿剂。

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