Cardiac effects of seasonal ambient particulate matter and ozone co-exposure in rats

摘要

Background The potential for seasonal differences in the physicochemical characteristics of ambient particulate matter (PM) to modify interactive effects with gaseous pollutants has not been thoroughly examined. The purpose of this study was to compare cardiac responses in conscious hypertensive rats co-exposed to concentrated ambient particulates (CAPs) and ozone (O₃) in Durham, NC during the summer and winter, and to analyze responses based on particle mass and chemistry.