Pulsed Radiofrequency Treatment for Chronic Post-Surgical Orchialgia: A Double-Blind, Sham-Controlled, Randomized Trial: Three-Month Results

摘要

Background: Chronic post-surgical pain in the groin region represents a challenge for themanaging physician and is a burden on the quality of life of the patient. None of the existinginterventions or medical treatment is satisfactory.Objectives: We aim to evaluate the analgesic efficacy of pulsed radiofrequency (PRF) applied tothe ilioinguinal nerve and the genital branch of the genitofemoral nerve for patients suffering fromchronic post-surgical orchialgia.Study Design: A prospective randomized, controlled clinical trial.Settings: An interventional pain unit in a tertiary center at a university hospital in Egypt.Methods: Seventy patients complaining of chronic post-surgical orchialgia were randomized into2 groups: PRF group (n = 35), received pulsed radiofrequency on the ilioinguinal nerve and genitalbranch of the genitofemoral nerve, or sham group (n = 35). The percentage of patients thatshowed > 50 % reduction of their visual analog scale (VAS) pain score as well as the percentage ofpatients that did not require additional analgesic drugs was assessed. The VAS pain score and theglobal perceived effect (GPE) were reported during the 3-month follow-up period.Results: The percentage of patients that showed > 50% reduction of their VAS pain score was80% (24/30) in the PRF group versus 23.33% (7/30) in the sham group. The percentage of patientsthat did not require analgesic drugs was 50% (15/30) in the PRF group versus 3.3% (1/30) in thesham group. There was a significant reduction of the mean post-procedural VAS pain score at 2,4, 6, 8, and 12 weeks (P = 0.001) in the PRF group in comparison to the sham group. Likewise,there was a significant improvement of the GPE in the PRF group in comparison to the sham group(P = 0.00).Limitations: The study’s follow-up period was limited to 3 months only.Conclusions: For patients suffering from chronic post-surgical orchialgia, PRF applied to theilioinguinal nerve and the genital branch of the genitofemoral nerve is an effective treatmentmodality. It provides long-lasting pain relief and decreases the demand for pain medications.