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Correlation between microalbuminuria and hypertension in Type 2 diabetic patients

机译:2型糖尿病患者微量白蛋白尿与高血压的相关性

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Background: Hypertension is commonly found in patients with Diabetic Kidney Disease (DKD). Microalbuminuria is the first clinical sign of involvement of kidneys in patients with type 2 diabetes. Uncontrolled hypertension induces a higher risk of cardiovascular events, including death, increasing proteinuria and progression to kidney disease.Objectives: To determine the correlation between microalbuminuria and hypertension and their association with other risk factors in type 2 diabetic patients.Methods: One hundred and thirteen type 2 diabetic patients attending the diabetic clinic of Shaikh Zayed Postgraduate Medical Institute, Lahore, Pakistan were screened for microalbuminuria and raised blood pressure. The study was conducted from November 2012 to June 2013.Results: Patients were divided into two groups. Group 1, those with normoalbuminuria (n=63) and Group 2, those having microalbuminuria (n=50). Group 2 patients showed higher blood pressure values as compared to Group 1. The results were statistically significant and showed poor glycemic control as a contributing risk factor.Conclusion: The study concluded that there is high frequency of hypertension among type 2 diabetics but still much higher among those having microalbuminuria. So, early recognition of renal dysfunction through detection of microalbuminuria and to start treatment without any delay will confer future protection from end stage renal disease as well as hypertension and its complications in type 2 diabetic patients.doi: http://dx.doi.org/10.12669/pjms.303.5042How to cite this:Ali A, Taj A, Amin MJ, Iqbal F, Iqbal Z. Correlation between microalbuminuria and hypertension in Type 2 diabetic patients. Pak J Med Sci 2014;30(3):511-514. doi: http://dx.doi.org/10.12669/pjms.303.5042This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
机译:背景:高血压常见于糖尿病肾病(DKD)患者中。微量白蛋白尿是2型糖尿病患者肾脏受累的第一个临床标志。目的:确定2型糖尿病患者中微量白蛋白尿与高血压之间的相关性,以及它们与其他危险因素的相关性。方法:不受控制的高血压诱发心血管事件的更高风险,包括死亡,蛋白尿增加和发展为肾脏疾病。方法:113对在巴基斯坦拉合尔的谢赫·扎耶德研究生医学研究所的糖尿病门诊就诊的2型糖尿病患者进行了微量白蛋白尿筛查和血压升高。该研究于2012年11月至2013年6月进行。结果:将患者分为两组。第1组患有白蛋白尿(n = 63),第2组患有微量白蛋白尿(n = 50)。与第1组相比,第2组患者的血压值更高。结果具有统计学意义,并且血糖控制不良是导致危险的危险因素。结论:该研究得出结论,2型糖尿病患者中高血压的发生率较高,但仍然更高在那些有微量白蛋白尿的人群中。因此,通过检测微量白蛋白尿及尽早开始治疗来早期识别肾功能不全,将为将来的终末期肾脏疾病以及2型糖尿病患者的高血压及其并发症提供保护。doi:http://dx.doi。 org / 10.12669 / pjms.303.5042如何引用此信息:Ali A,Taj A,Amin MJ,Iqbal F,IqbalZ。2型糖尿病患者微量白蛋白尿与高血压的相关性。 Pak J Med Sci 2014; 30(3):511-514。 doi:http://dx.doi.org/10.12669/pjms.303.5042这是根据知识共享署名许可(http://creativecommons.org/licenses/by/3.0)的条款分发的开放访问文章,只要适当引用了原始作品,便可以在任何介质中不受限制地使用,分发和复制。

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