The extracts of the four biologically active medicinal plants Grewia erythraea, Hymenocrater sessilifolius, Vincetoxicum stocksii and Zygophyllum fabago were evaluated for their cytotoxicity. These plants are used in folk medicine but their scientific toxicity is not well established. The cytotoxicity of the six fractions of plant extracts was determined by flow cytometry on 2 × 106 CFU/ml of C. albicans at different concentrations of extracts for a period of 1, 2, and 24 h at 25oC. The 1 h exposure showed that 1.0 g/ml extract of Z. fabago killed 98% of cells; V. stocksii killed 60%; H. sessilifolius 29% and G. erythraea only 2%. Similar results were obtained when the cytotoxicity was also checked through brine shrimps (Artemia salina) cytotoxicity assay. The chloroform fractions of all the extracts were most effective.
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机译：评估了四种具有生物活性的药用植物Grewia erythraea，Hymenocrater sessilifolius，Vincetoxicum stocksii和Zygophyllum fabago的提取物的细胞毒性。这些植物用于民间医学，但其科学毒性尚不充分。通过流式细胞术在25°C下分别以2×106 CFU / ml的白色念珠菌以不同浓度的提取物通过流式细胞术测定六种植物提取物的细胞毒性。暴露1小时表明，1.0克/毫升的法氏酵母提取物杀死了98％的细胞。 V. stocksii杀死60％; sessilifolius H. 29％和G. erythraea仅2％。当还通过盐水虾（卤虫）的细胞毒性测定检查细胞毒性时，获得了相似的结果。所有提取物中的氯仿馏分最为有效。
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