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A case of successfully resected metachronous gastric and gallbladder metastases from pancreatic body cancer

机译:胰腺癌成功切除异时胃,胆囊转移的一例

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Abstract BackgroundPancreatic ductal adenocarcinoma (PDAC) readily metastasizes to the lymph nodes, liver, lung, and peritoneum; however, gastric and gallbladder metastases are rare. We report a case of metachronous gastric and gallbladder metastases from PDAC.Case presentationThe patient is a 71-year-old man who underwent distal pancreatectomy for PDAC. Seventeen months after the surgery, a 30-mm nodule was detected at the lesser curvature of the stomach, which was diagnosed as recurrence of PDAC in the lymph nodes. He then received gemcitabine and S-1 combination chemotherapy for 6?months. Because tumor size remained approximately the same and tumor marker levels decreased, total gastrectomy and cholecystectomy were performed. Pathological examination showed well-differentiated tubular adenocarcinoma in the subserosa and muscularis propria of the stomach and gallbladder. The patient remains alive at 41?months after the second surgery with liver metastasis.ConclusionWe reported a rare case of metachronous gastric and gallbladder metastases from pancreatic body cancer.
机译:胰腺导管腺癌(PDAC)易于转移至淋巴结,肝,肺和腹膜。但是,胃和胆囊转移很少。我们报告了一例从PDAC转移到胃和胆囊的病例。病例介绍该患者是一名71岁的男性,接受了PDAC远端胰腺切除术。手术后十七个月,在胃小弯处发现了一个30毫米的结节,被诊断为PDAC在淋巴结中复发。然后,他接受了吉西他滨和S-1联合化疗6个月。由于肿瘤大小保持大致相同且肿瘤标志物水平降低,因此进行了全胃切除术和胆囊切除术。病理检查显示,胃和胆囊的浆膜下和固有层肌管分化良好。该患者在第二次肝转移手术后41个月仍存活。结论我们报告了一例罕见的胰腺癌同时发生胃和胆囊转移的病例。

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