Stem cell plasticity (Systematic review)

摘要

Objective: To study stem cell plasticity and its role in the treatment of different diseases. Data sources : MEDLINE, EMBASE and PUBMED databases were searched. The search was performed on 1 October 2014 and included articles published ahead of print with no language restrictions. Study selection: The initial search presented 500 articles, papers and journals about stem cells, stem cell therapy and Stem cell plasticity. Data extraction : Data from each eligible study were independently abstracted in duplicate using a data collection form to capture information on study characteristics, interventions, quantitative results reported for each outcome of interest. Data synthesis: Because of heterogencity of stem cells, stem cell therapy and stem cell plasticity and outcome measures reported, it was not possible to pool the data and carry out a meta-analysis. Significant data were collected . Thus, a structured review was performed. Conclusion: Excellent outcomes have been achieved in the field of stem cell plasticity and Stem cell therapy of several diseases such as diabetes mellitus, stroke, cardiovascular Diseases, hepatic diseases and neurodegenerative diseases.