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Application of umbilical cord blood stem cell transplantation: A better option in regenerative medicine

机译:脐血干细胞移植的应用:再生医学的更好选择

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Extensive research in the field of stem cells has proven the possibility of repairing the damaged tissues and organs. Stem cells can divide and differentiate into various specialized cells. In adult organisms, stem cells act by repairing adult tissues and in a developing embryo, they not only differentiate into all the specialized cells, but also maintain the normal turnover of regenerative organs.Unfortunately the application of stem cells as a therapeutic intervention is in the early stages because the development of stem cells requires ethically sound and scientifically robust models. In recent years, however, the stem-cell rich blood of umbilical cord has shown immense use compared to using bone marrow stem cells and peripheral blood stem cells. The versatility and availability of umbilical cord blood stem cells makes them a potent resource for transplant therapies. The peripheral blood stem cells can be used just like bone marrow stem cells to treat leukemia, other cancers and various blood disorders. In this review article we present an overview of the significant scientific aspects of using human umbilical cord blood stem cells, their biological role and potential regenerative property.  
机译:干细胞领域的广泛研究证明了修复受损组织和器官的可能性。干细胞可以分裂并分化成各种专门的细胞。在成年生物中,干细胞通过修复成年组织而起作用,并且在发育中的胚胎中,它们不仅分化为所有特化细胞,而且还能维持再生器官的正常更新。不幸的是,干细胞在治疗中的应用是早期阶段是因为干细胞的发育需要符合道德规范和科学稳健的模型。然而,近年来,与使用骨髓干细胞和外周血干细胞相比,脐带血富含干细胞已显示出巨大的用途。脐带血干细胞的多功能性和可用性使它们成为移植疗法的强大资源。外周血干细胞可以像骨髓干细胞一样用于治疗白血病,其他癌症和各种血液疾病。在这篇综述文章中,我们概述了使用人脐带血干细胞的重要科学方面,其生物学作用和潜在的再生特性。  

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