A case of vitiligo with hypertrophic lichen planus – an autoimmune association

摘要

Vitiligo is a common autoimmune dermatological disorder characterized by depigmentation of the skin and mucous membranes. It has been associated with a variety of autoimmune disorders. A 54 years old male patient presented with depigmented patches over the legs for 30 years and itchy hyperpigmented plaques over the forehead for past 2 months. Patient had history of recurrent oral ulcers and history of psychological stress. Cutaneous examination revealed two well defined depigmented patches over the shin of both legs, and over lower lip. There were multiple hyperpigmented violaceous plaques over the forehead, right side cheek and scalp. White streaks were present over the buccal mucosa. Biopsy report for the hyperpigmented plaques was consistent with hypertrophic lichen planus and depigmented patch was consistent with vitiligo. Though the aetiology of vitiligo and lichen planus is not known with certainty, its coexistence has been scarcely reported in the literature suggesting a common autoimmune aetiology.