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Bilateral Fibular Graft: Biological Reconstruction after Resection of Primary Malignant Bone Tumors of the Lower Limb

机译:双侧腓骨移植:下肢原发性恶性骨肿瘤切除术后的生物学重建

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This paper deals with bilateral vascularized fibular grafts (BVFG) as a method for reconstruction of metadiaphyseal defects of the femur and tibia in young patients suffering from malignant bone tumors of the lower limb. This reconstructional technique was used in 11 patients undergoing metadiaphyseal resection of lower limb malignant bone tumors. All patients with Ewing’s sarcoma and osteosarcoma had multimodal treatment according to the EURO-E.W.I.N.G 99 or COSS-96 protocol. Median FU was 63 months. None of the patients experienced local recurrence during FU. 2 patients died due to distant disease during FU. Full weight- bearing was permitted after a mean of 8 months. The median MSTS score was 87%. Complications occurred in five patients. None of the complications led to failure of the biological reconstruction or to amputation. Biological reconstruction of osseous defects is always desirable when possible and aims at a permanent solution. Good functional and durable results can be obtained by using BVFG for the reconstruction of metadiaphyseal defects of the femur and tibia. Radiotherapy in the multimodal setting increases the risk for graft or fixation failure.
机译:本文探讨双侧血管化腓骨移植(BVFG)作为一种重建下肢恶性骨肿瘤青年患者股骨和胫骨干dia端缺损的方法。该重建技术用于11例下肢恶性骨肿瘤干meta端切除术患者。根据EURO-E.W.I.N.G 99或COSS-96协议,所有尤因肉瘤和骨肉瘤患者均接受了多模式治疗。中位FU为63个月。所有患者在FU期间均未出现局部复发。 2例患者在FU期间因远处疾病死亡。平均8个月后允许完全负重。 MSTS中位数得分为87%。 5例患者发生并发症。这些并发症均未导致生物学重建失败或截肢。在可能的情况下,总是希望对骨缺损进行生物重建,并寻求永久解决方案。通过使用BVFG重建股骨和胫骨干dia端缺损,可以获得良好的功能性和持久性结果。在多模式环境中进行放射治疗会增加移植或固定失败的风险。

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