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CUTANEOUS TB PROFILE IN NORTH WEST PUNJAB, INDIA: A RETROSPECTIVE DATA ANALYSIS

机译:印度西北旁遮普省的结核病现况:回顾性数据分析

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Although it is a "disease of antiquity", nicely described by Kaur T et al, tuberculosis is still a challenge in the modern medicine. The authors highlighted the role of HIV coinfection, but we don't have to forget about the role of anti-TNF therapies (widely prescribed nowadays) in reactivating tuberculosis infection, especially in endemic regions [1].Another important point that we could observe here is the important number of cases with a negative Mantoux test (approximately 36%). As we showed previously, Mantoux or tuberculin skin test (TST) is not a reliable technique in detecting the infection. We registered positive tuberculin skin test (defined in the context of biologic therapy as induration >5 mm) in 51% of nondermatologic subjects, respectively 70% of the patients with psoriasis [2]. Among them, 50% of psoriatic patients and 28% of nondermatologic subjects had an induration >10 mm (unpublished data).
机译:尽管这是Kaur T等人很好地描述的“古代疾病”,但结核病仍然是现代医学中的一个挑战。作者强调了HIV合并感染的作用,但我们不必忘记抗TNF治疗(如今已广泛使用)在重新激活结核病感染中的作用,尤其是在流行地区[1]。我们可以观察到的另一个重要点这是Mantoux检验为阴性(约36%)的重要病例数。如我们先前所示,Mantoux或结核菌素皮肤测试(TST)在检测感染方面不是可靠的技术。我们在51%的非皮肤科受试者和70%的牛皮癣患者中注册了结核菌素皮肤试验阳性(在生物治疗中定义为硬结> 5 mm)[2]。其中,50%的银屑病患者和28%的非皮肤科受试者的硬结> 10 mm(未发表数据)。

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