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Rotator cuff repair: challenges and solutions

机译:肩袖修复:挑战与解决方案

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Abstract: Each year, 250,000 rotator cuff repairs are performed in the United States at a cost of $3 billion. Despite advancements in repair techniques and rehabilitation, 20%–70% of repairs continue to undergo structural failure; however, there is a poor correlation between clinical and structural outcomes, both before and after surgery. "Failure in continuity", or retraction of the repair site without a structural defect, is likely a common phenomenon after rotator cuff repair, and this retraction of the myotendinous unit and interposing scar tissue may be one explanation for the discordance between clinical and structural outcomes. Scaffolds, both synthetic and biologic, have shown promise in both augmentation of repairs and interposition of irreparable tears, but most studies are small retrospective case series without control groups. Future efforts will need to determine the ideal indications for use, methods of application, and comparative effectiveness between the devices. Platelet-rich plasma also has potential to improve rotator cuff healing, but current limitations include the significant variation in preparation methods, biologic makeup, and application methods. Future work may help us understand whether application of platelet-rich plasma and its growth factors should be done at the time of surgery or later during a more advanced stage of healing. Regardless of the device or technique, mechanical and/or biologic augmentation of rotator cuff repairs requires the surgeon to be technically proficient in its use and aware of its associated increased operative time and cost. In order to justify the use of these technologies and their associated incremental cost, we must demonstrate efficacy in improving both clinical and structural outcomes.
机译:摘要:每年在美国进行250,000例肩袖修复,费用为30亿美元。尽管维修技术和康复技术有所进步,但仍有20%–70%的维修继续发生结构性故障。然而,在手术前后,临床和结构结果之间的相关性很差。转子套修复后,“连续性失败”或无结构缺陷的修复部位的回缩很可能是一种常见现象,而肌腱组织的这种回缩和插入的瘢痕组织可能是临床和结构结果之间不一致的一种解释。 。合成和生物支架在增加修复和插入不可修复的眼泪方面都显示出了希望,但是大多数研究都是小型回顾性病例组,没有对照组。未来的工作将需要确定理想的使用指示,使用方法以及设备之间的相对有效性。富含血小板的血浆还具有改善肩袖愈合的潜力,但目前的局限性包括制备方法,生物成分和应用方法的重大差异。未来的工作可能会帮助我们了解,应在手术时还是在更晚期的康复阶段中应用富含血小板的血浆及其生长因子。无论采用何种设备或技术,对转子套的机械和/或生物修复都需要外科医生在技术上精通其使用,并意识到其相关的增加的手术时间和成本。为了证明使用这些技术及其相关的增加成本的合理性,我们必须证明在改善临床和结构结局方面的功效。

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