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Post-transplant lymphoproliferative disorder presenting on post-transplant Day 35 as a pulmonary parenchymal infiltrate—a case report

机译:移植后第35天出现肺实质浸润的移植后淋巴增生性疾病-病例报告

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Post-transplant lymphoproliferative disorder (PTLD), a rare but serious complication of solid organ transplantation, is classified into early-onset and late-onset subtypes. Early-onset PTLD occurs a median of 4–11 months after lung transplantation. It rarely presents in the first 2 months post-transplant. Early-onset PTLD usually presents as a solitary pulmonary nodule. We present a unique case of early-onset PTLD that was diagnosed on post-operative Day 35 and presented as a pulmonary parenchymal infiltrate. This case is also exceptional in that the patient had a significant clinical response to only a single dose of rituximab.
机译:移植后淋巴细胞增生性疾病(PTLD)是实体器官移植的一种罕见但严重的并发症,分为早期发作和晚期发作亚型。肺移植后中位数为4-11个月,为早发性PTLD。它很少在移植后的前两个月出现。早发性PTLD通常表现为孤立性肺结节。我们介绍了在术后第35天被诊断出并表现为肺实质浸润的早期PTLD的独特病例。这种情况也是例外的,因为该患者仅对单剂量的利妥昔单抗具有显着的临床反应。

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